Method for preparing HA degradable coating on surface of magnesium alloy

Abstract

The invention discloses a method for preparing an HA degradable coating on the surface of magnesium alloy in the technical field of biological medicine. The method comprises the following concretely steps of S1, treating magnesium alloy base bodies; S2, preparing a sodium titanate solution; S3, preparing a transition layer on the magnesium alloy; S4, preparing nanometer antibacterial hydroxyapatite powder; S5, preparing a finished product. An HA coating grows on the surface of the magnesium alloy; the biological properties of the HA coating and the mechanical properties of the magnesium alloycan be simultaneously realized; the biological combination can be performed with bone tissues; nontoxicity is realized; harmful tissues cannot be generated; after being implemented into the human body, strong adhesion can be realized in a short time; the initial position fixation of implanting materials can be facilitated; in addition, antibacterial agents are added into the HA coating; the antibacterial cavity of the coating can be improved; the occurrence rate of the peri-implant inflammation can be reduced; the extensibility of the coating is good; good cellular morphology and proliferationrate are realized; good cell compatibility is realized.

Description

technical field [0001] The invention discloses a method for preparing a HA degradable coating on the surface of a magnesium alloy, specifically in the technical field of biomedicine. Background technique [0002] The bioceramic coating on the surface of magnesium alloy has been widely used as implant material because of its excellent biological properties. Currently, the commonly used material is hydroxyapatite, but due to its coating process and the stability of HA, the The HA coating dissolves rapidly in the body and leads to the failure of the implant. At the same time, the cytocompatibility between the HA coating and osteoblasts is not high, the HA coating is easy to fall off, and the stretchability on the surface of the material is poor. For this reason, we propose a method to prepare HA degradable coating on the surface of magnesium alloy and put it into use to solve the above problems. Contents of the invention [0003] The purpose of the present invention is to pr...

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Problems solved by technology

[0002] The bioceramic coating on the surface of magnesium alloy has been widely used as implant material because of its excellent biological properties. Currently, the commonly used material is hydroxyapatite, but due to its coating process and the stability of HA, the The HA coating dissolves rapidly in the body, which leads to the failure of the implant. At the same time, the cytocompatibility between the HA coating and osteoblasts is not high, the HA coating is easy to fall off, and the stretchability on the surface of the material is poor.