8 results about "Ha coating" patented technology

The HA coating PEEK anchor with the expansion wings comprises an anchor body, the head of the anchor body is in a conical tip shape, the outer wall of the anchor body of the anchor body is provided with a barb structure, and the tail of the anchor body is provided with a fastening channel extending in the axial direction of the anchor body. A plurality of wing penetrating channels which penetrate through a rivet body and are communicated with the fastening channel are formed in the rivet body of the rivet body, expansion wings are movably installed in the wing penetrating channels, and ejection screws used for ejecting the expansion wings out of the wing penetrating channels are movably installed in the fastening channel. The outer surface of the anchor main body is coated with an HA coating; and the anchor main body, the expansion wings and the ejection screw are PEEK bodies. Expansion of the expansion wings can be achieved through axial movement of the ejection screw, and the expansion degree of the expansion wings can be increased by rotating the hexagonal driving part. On one hand, the fixing strength of the anchor is improved to a great extent, and on the other hand, the anchor can be suitable for different bone conditions and is particularly suitable for patients with osteoporosis or undetailed bone conditions to a great extent.

The application discloses a preparation method of a 3D printing hip joint stress relief heat treatment double-gradient bone support, and the method comprises the following steps: acquiring image data by performing three-dimensional scanning on a bone defect by means of a CT scanning device, designing the size and shape of a transplantable bone, designing a concave hexagonal support structure with gradient porosity by means of UG three-dimensional drawing software, and gradually transitioning from a Ti-35Nb-5Ta-7Zr alloy with good biocompatibility and a low elastic modulus to a Co-Cr-Mo alloy with good wear resistance and corrosion resistance, improving metallurgical incompatibility, obtaining better interface combination, minimizing bone resorption and aseptic loosening caused by wear, prolonging the service life of an implant, and performing annealing heat treatment on the functional support after printing to eliminate residual stress and depositing a HA coating to enhance cell activity.

The application discloses a kind of micelles LYTAC engineering biomimetic titanium implants for promoting bone regeneration and its preparation method and application, belong to biomimetic medical instrument technical field.The micelles LYTAC engineering biomimetic titanium implants include titanium matrix, hydroxyapatite coating formed on the surface of the titanium matrix, and multifunctional micelles loaded in the hydroxyapatite coating;The multifunctional micelles include CLP-Apt complex, and the CLP-Apt complex is formed by covalent connection of collagen-like peptide CLP and RANK-CI-M6PR bispecific aptamer Apt through acid-sensitive linker.The application applies LYTAC technology to the surface of titanium implant by constructing HA coating loaded with CLP-Apt micelles.Experiments in vitro and in vivo show that it significantly improves the effect of bone integration under osteoporosis condition, and provides an effective scheme for long-term stability of clinical implant.

The invention provides a preparation method of a gradient biological coating with a controllable structure, which comprises the following steps: step 1, preparing uniformly mixed TC4 / HA powder by utilizing a low-energy ball milling method before coating deposition; 2, a TC4 / HA coating for relieving the thermal expansion coefficient is prepared on the surface of the titanium alloy through the atmosphere plasma spraying technology; and 3, preheating the base material deposited with the TC4 / HA transition layer, and preparing the HA biological coating with a controllable structure on the surface of the TC4 / HA coating.

This invention discloses a three-layered functional hydrogel material for osteochondral repair that promotes chondrogenesis through traditional Chinese medicine and physical stimulation, and its preparation method. Specifically, the method includes: 1) preparing a PCL electrospun membrane using electrospinning technology, and forming an HA coating on its surface using a hydrothermal method with biomimetic mineralization; 2) constructing the HA coating on the surface of black phosphorus sheets and preparing cryptotanshinone nanopowder using in-situ mineralization and spraying methods, and mixing it with BMSCs in a porous GelMA solution; 3) preparing MCSN nanoparticles loaded with baicalein using a hydrothermal template method and ultrasonic impregnation process; 4) dispersing barium titanate nanowires, drug-loaded MCSN, and BMSCs in a SilMA / HAMA solution; 5) pouring the GelMA mixture into a mold and pre-curing it, placing a plasma-treated mineralized electrospun membrane on top, then pouring the SilMA / HAMA mixture and completely curing it to obtain the desired hydrogel. This composite material has a three-layer structure, matching the needs of osteochondral repair.

This utility model belongs to the field of bone screws, specifically a bone screw structure. Addressing the issue that existing traditional dental bone screws have a smooth metal surface between the threads, which leads to poor contact between the smooth metal surface and bone tissue during installation, creating micro-gaps that facilitate bacterial colonization and can cause infection and inflammation, the proposed solution includes a bone screw body made of titanium alloy. The bottom outer surface of the bone screw body is coated with an HA coating, and the bottom outer surface of the bone screw body has threads for easy installation and fixation. The HA coating and reinforcing mechanism increase the contact area and friction between the bone screw and bone tissue. This design allows the bone screw to fit more tightly with the bone tissue after implantation, effectively reducing the formation of micro-gaps, thereby significantly improving the stability of the bone screw in the bone tissue, reducing the risk of loosening, and providing reliable anchorage for subsequent oral treatments (such as orthodontics).

This utility model discloses an expandable HA-coated PEEK knotless anchor, comprising an anchor body with barbed structures on the outer wall of the anchor body and an axially extending operating channel. Within the operating channel is a support member that can move axially along the anchor body. At least two support plates are provided at the head end of the anchor body, with the inner walls of the support plates tightly abutting the outer walls of the support members. A threading head is provided at the end of the support member near the head end of the anchor body, with a through-hole for threading sutures. When the support member moves towards the tail end of the anchor body under external force, the support plates are compressed by the outer walls of the support member and expand outwards to compress the suture. The axial movement of the support member drives the expansion of the support plates, which helps to strengthen the compression and fixation of the suture, thereby improving the reliability and fatigue load resistance of the knotless anchor. The HA coating on the surface improves the biocompatibility and new bone growth effect of the anchor.

The invention discloses a micelle LYTAC engineering bionic titanium implant for promoting bone regeneration as well as a preparation method and application of the micelle LYTAC engineering bionic titanium implant, and belongs to the technical field of bionic medical instruments. The micelle LYTAC engineering bionic titanium implant comprises a titanium substrate, a hydroxyapatite coating formed on the surface of the titanium substrate, and a multifunctional micelle loaded in the hydroxyapatite coating, the multifunctional micelle comprises a CLP-Apt compound, and the CLP-Apt compound is formed by covalent linkage of a collagen-like peptide CLP and an RANK-CI-M6PR bispecific aptamer Apt through an acid sensitive connexon. According to the invention, the LYTAC technology is applied to the surface of the titanium implant by constructing the HA coating loaded with the CLP-Apt micelle. In-vivo and in-vitro experiments show that the osseointegration effect is remarkably improved under the osteoporosis condition, and an effective scheme is provided for long-term stability of clinical implants.