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Electrospinning receiving device, method for preparing oriented electrospinning tubular scaffold and tubular scaffold

A technology of electrospinning and receiving devices, applied in textiles and papermaking, filament/thread forming, fiber processing, etc., can solve problems that cannot meet actual clinical needs

Active Publication Date: 2021-05-18
MEDPRIN REGENERATIVE MEDICAL TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The above two preparation methods can only obtain tubular stents oriented in one direction, which cannot meet the actual clinical needs, and there is currently no spinning equipment that can obtain both radially oriented tubular stents and axially oriented tubular stents on the same equipment. Function of various monopolar tubular stents in stents or other angular orientations

Method used

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  • Electrospinning receiving device, method for preparing oriented electrospinning tubular scaffold and tubular scaffold
  • Electrospinning receiving device, method for preparing oriented electrospinning tubular scaffold and tubular scaffold
  • Electrospinning receiving device, method for preparing oriented electrospinning tubular scaffold and tubular scaffold

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0044] An electrospinning receiving device, which specifically includes a first receiving rod 1, a second receiving rod 2, a third receiving rod 3, a rotating rod 4, a high-voltage distribution unit and a first drive unit 5; the second receiving rod The rod 2 is arranged in parallel with the rotating rod 4, and the first receiving rod 1 and the third receiving rod 3 are arranged in parallel; the first receiving rod 1, the second receiving rod 2, the third receiving rod 3 and the rotating rod 4 are connected end to end The parts are connected, and form a parallelogram area on the same plane, and the parallelogram area is called the receiving surface; the first driving unit 5 can drive the rotating rod 4 to rotate along its central axis, and the rotating rod 4 and the first The receiving rod 1, the second receiving rod 2, and the third receiving rod 3 are respectively connected to a high-voltage distribution unit, and the high-voltage distribution unit can adjust the voltage on t...

Embodiment 2

[0048] The second receiving rod 2 and the rotating rod 4 are capable of relative translational movement along their axial directions. In this embodiment, there are many ways to realize the relative translational movement between the second receiving rod 2 and the rotating rod 4. It can be to drive the rotating rod 4 and / or the second receiving rod 2 to make a translational movement along its axial direction, or It may be to drive the first receiving rod 1 and / or the third receiving rod 3 to swing and then drive the second receiving rod 2 and the rotating rod 4 to perform relative translational movement.

[0049] Other parts of this embodiment are the same as those of Embodiment 1, and will not be repeated here.

Embodiment 3

[0051] The electrospinning receiving device can also include a first support 61, a second support 62, a third support 71 and a fourth support 72; The upper end bearing is connected; the two ends of the first receiving rod 1 are respectively connected with the upper ends of the first bracket 61 and the third bracket 71 through a spherical hinge; the two ends of the second receiving rod 2 are connected with the third bracket 71 and the third bracket 71 respectively The upper ends of four brackets 72 are connected by spherical hinges; the two ends of the third receiving rod 3 are respectively connected with the second bracket 62 and the fourth bracket 72 by spherical hinges; The synchronous movement in the linear direction enables relative translational movement between the second receiving rod 2 and the rotating rod 4 along their axial directions. Wherein, the first, second and third receiving rods are connected with the first, second, third and fourth brackets through spherical...

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Abstract

The invention relates to an electrospinning receiving device, a method for preparing an oriented electrospinning tubular support and a tubular support. The electrospinning receiving device includes a receiving surface, a first driving unit and a high-voltage distribution unit. The receiving surface is composed of a first receiving rod, the second receiving rod, the third receiving rod and the rotating rod connected end to end to form a parallelogram area, the first driving unit is connected with the rotating rod, and drives the rotating rod to rotate along its central axis; the high pressure The distribution unit controls voltages of the first receiving rod, the second receiving rod, the third receiving rod and the rotating rod. The electrospinning receiving device can obtain multi-orientation monopolar tubular stents and multi-polar oriented tubular stents on the same receiving device, and the prepared tubular stents are integrally formed, there is no bonding weak point, and the mechanical properties are excellent .

Description

technical field [0001] The invention relates to the technical field of electrospinning, and more specifically, to an electrospinning receiving device, a method for preparing an oriented electrospinning tubular support and the tubular support. Background technique [0002] At present, electrospinning technology is a very effective method for preparing nanometer to micron-scale fibers. The equipment is simple and inexpensive, and the prepared tissue engineering scaffold has a high specific surface area, and the diameter and porosity of the nanofibers can be controlled. In particular, the three-dimensional network structure similar to the natural extracellular matrix can be obtained, so it is widely used in the preparation of tissue engineering scaffolds. In most cases, the scaffolds prepared by using static collectors are mostly flat sheet membranes. [0003] Since many tissues in the human body, such as blood vessels, neural tubes, ureters, etc. The prepared tubular stent o...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): D01D5/00
CPCD01D5/0076
Inventor 张海涛邓坤学袁玉宇
Owner MEDPRIN REGENERATIVE MEDICAL TECH