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Preparation method of chiral supramolecular hydrogel skin ointment for bacteriostatic repair

A supramolecular hydrogel and chiral technology, applied in skin diseases, ointment delivery, medical preparations containing active ingredients, etc., can solve problems such as long course of disease, many complications, affecting the health and quality of life of patients, and achieve The ingredients are smooth and moisturizing, it can be used in a wide range of places, and it can maintain the antibacterial and repairing effect for a long time

Inactive Publication Date: 2018-11-30
海安百优基质生物工程有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Due to the long course of wound healing and many complications, it seriously affects the health and quality of life of patients and brings a huge burden to the society.

Method used

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  • Preparation method of chiral supramolecular hydrogel skin ointment for bacteriostatic repair
  • Preparation method of chiral supramolecular hydrogel skin ointment for bacteriostatic repair
  • Preparation method of chiral supramolecular hydrogel skin ointment for bacteriostatic repair

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0013] Ointment formulation:

[0014]

[0015] Preparation process: take the chiral supramolecular hydrogel factor in a container and dissolve it in pure water at 80-90°C for 5 minutes; take another grain worm extract and add pure water and stir it at room temperature for 10 minutes to dissolve; take borneol and add pure water at 60-80°C and stir until completely dissolved; take another natural beeswax and liquid paraffin in another container, and heat at 40-50°C until completely melted. Finally, slowly add the water phase liquid into the oil phase liquid and mix, and keep stirring until the final shape is obtained.

Embodiment 2

[0017] Ointment formulation:

[0018]

[0019] Preparation process: take the chiral supramolecular hydrogel factor in a container and dissolve it in pure water at 80-90°C for 5 minutes; take another grain worm extract and add pure water and stir it at room temperature for 10 minutes to dissolve; take borneol and add pure water at 60-80°C and stir until completely dissolved; take another natural beeswax and liquid paraffin in another container, and heat at 40-50°C until completely melted. Finally, slowly add the water phase liquid into the oil phase liquid and mix, and keep stirring until the final shape is obtained.

Embodiment 3

[0021] Ointment formulation:

[0022]

[0023] Preparation process: take the chiral supramolecular hydrogel factor in a container and dissolve it in pure water at 80-90°C for 5 minutes; take another grain worm extract and add pure water and stir it at room temperature for 10 minutes to dissolve; take borneol and add pure water at 60-80°C and stir until completely dissolved; take another natural beeswax and liquid paraffin in another container, and heat at 40-50°C until completely melted. Finally, slowly add the water phase liquid into the oil phase liquid and mix, and keep stirring until the final shape is obtained.

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Abstract

The invention discloses a preparation method of a chiral supramolecular hydrogel skin ointment for bacteriostatic repair, which belongs to the technical field of a medicinal preparation. The preparation method comprises the following steps: respectively dissolving the chiral supramolecular hydrogel, a worm extract and borneol in pure water, respectively obtaining the chiral supramolecular hydrogelaqueous solution, a worm extract aqueous solution and a borneol aqueous solution, after beeswax and liquid paraffin are heated and melted, mixing the chiral supramolecular hydrogel solution, the wormextract aqueous solution and the borneol aqueous solution, and stirring a mixture to a shaping state to obtain the chiral supramolecular hydrogel skin ointment for bacteriostatic repair. The productdoes not contain hormones and has no toxic or side effects, can be applied to a wide range of uses, and can effectively inhibit the erosion of bacteria on the skin and further achieve the repair effect. The product components are mild, smooth and moist, and can maintain the antibacterial repair effect while lubricating and moisturizing.

Description

technical field [0001] The invention belongs to the technical field of pharmaceutical preparations, and in particular relates to a preparation method of a chiral supramolecular hydrogel skin ointment for antibacterial repair. Background technique [0002] There have been a large number of reports on antibacterial agents for skin, and there are currently many products on the market, such as hydroxychloroquine, dapsone and acetidine, etc., which can be used as skin antibacterial agents, and have been favored by many scientific researchers. Concerned and researched, the invention patent application with application number 201310338452.6 provides a skin antibacterial agent mainly composed of bornyl fennel alcohol, a saponification product of bornyl oxalate, and the invention patent with application number 200810072492.X provides a Bacteriostatic agents mainly come from plants, such as aloe, comfrey, pearl powder, hives, medicinal oils, and substrates. However, most of the produc...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K35/64A61K31/045A61K9/06A61K47/44A61K47/06A61P17/02A61P31/02
CPCA61K47/06A61K47/44A61P17/02A61P31/02A61K9/0014A61K9/06A61K31/045A61K35/63A61K2300/00
Inventor 王蓉冯传良郑丽红刘子铖
Owner 海安百优基质生物工程有限公司
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