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A Method for Measuring Retinal Vessel Wall Thickness Based on Image Registration

A technique for retinal blood vessels and image registration, applied in the field of image processing, to achieve the effects of improving accuracy, saving time, and improving accuracy

Active Publication Date: 2020-05-08
UNIV OF ELECTRONICS SCI & TECH OF CHINA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

This is because when there is a problem with the thickness of a single vessel wall, it does not affect the average vessel wall thickness.

Method used

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  • A Method for Measuring Retinal Vessel Wall Thickness Based on Image Registration
  • A Method for Measuring Retinal Vessel Wall Thickness Based on Image Registration
  • A Method for Measuring Retinal Vessel Wall Thickness Based on Image Registration

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Experimental program
Comparison scheme
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Embodiment 1

[0078] This embodiment will first be described as follows:

[0079] The name used in the color fundus image is marked with serial number 1, and the name used in the fundus fluoroscopy image is marked with serial number 2; that is, 1 represents the fundus color image, and 2 represents the fundus fluorescein image.

[0080] The arrays in the embodiment can all be saved as images. In addition, the arrays that participate in the calculation in the next step can all be derived from the results in the previous step, or the result images generated in the previous step can be re-read. In addition, the following array and picture information storage results are stored in the order of A to Z, which has no practical meaning.

[0081] Such as figure 1 As shown, the method for measuring retinal vessel wall thickness based on multi-modal fundus image registration of the present invention includes the following steps:

[0082] S101: Input the fundus color image and the fundus fluorescence contrast i...

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Abstract

The invention relates to the field of image processing, and aims to disclose a method for measuring retinal vessel wall thickness based on image registration to solve the problems of low accuracy of existing registration methods and low accuracy of existing methods for measuring retinal vessel wall thickness; A new method for registration of fundus multimodal images and a new method for measuring the average thickness of retinal vessel wall and the thickness of a single vessel wall; the method includes: acquiring color fundus images and fundus fluorescein angiography images; Preprocessing, vessel segmentation, vessel denoising, vessel bone extraction, corner point detection, feature point generation; registration based on corner point features; optic disk labeling of registered pictures; measurement of vessel wall thickness. The invention can be used for clinical ophthalmology image analysis and result imaging, and is dedicated to assisting doctors in making judgments and saving doctors' time.

Description

Technical field [0001] The invention relates to the technical field of image processing, in particular to a method for measuring the thickness of retinal blood vessel walls based on image registration. Background technique [0002] The fundus retinal blood vessel is the only visible blood vessel in the human body. Doctors use it as a window to understand the blood vessels of other organs. For example, retinal arteriosclerosis can be seen in the fundus of hypertensive patients, capillary hemangioma, small bleeding points and exudates can be seen in the fundus of diabetic patients. The thickness of the fundus blood vessel wall can be used as an early indicator of diabetic retinopathy and help to judge the vascular and venous sclerosis. The fundus color image contains the outer side of the blood vessel wall, and the fundus fluorescein image only contains the inner side of the blood vessel. Registering the fundus image can make the information of the two images complementary and mak...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): G06T7/62G06T7/13G06T7/11G06T7/136G06T7/33G06T7/00G06K9/62
CPCG06T7/0012G06T7/11G06T7/13G06T7/136G06T7/337G06T7/62G06T2207/10064G06T2207/10024G06T2207/30041G06T2207/20164G06F18/2135
Inventor 秦臻陈硕秦志光丁熠周尔强邓伏虎赵洋
Owner UNIV OF ELECTRONICS SCI & TECH OF CHINA