Application of porcellio scaber latreille in preparation of medicines for treating diseases and symptoms of hyperthermia
A technology of sputum and body temperature, which is applied to the application field of sagebrush in the preparation of medicines for treating diseases and symptoms related to hyperthermia, and achieves the effects of simple and feasible preparation process, significant antipyretic effect, and inhibition of body temperature rise.
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Embodiment 1
[0019] Example 1: The antipyretic effect of chrysalis on lipopolysaccharide-induced fever rats.
[0020] 1. The preparation of the herbal medicinal material:
[0021] Use low heat to dry the mouse woman, and grind it into powder. Ratwort powder was directly mixed with normal saline, and ultrasonically treated for 15 minutes.
[0022] 2. Antipyretic experiment:
[0023] 60 qualified SD male rats were selected and randomly divided into 6 groups (blank control group, model group, positive control group, high-dose treatment group, medium-dose treatment group, and low-dose treatment group) in each group 10 only. The control group was administered with normal saline, the positive control group was administered with ibuprofen suspension (dose 1ml / (kg. times)), the experimental group was administered with Ratwo suspension, the high dose group was 0.2g / kg, the middle dose was 0.2g / kg. Group 0.1 g / kg, low dose group 0.05 g / kg. Male SD rats were fed at room temperature for three day...
Embodiment 2
[0030] Example 2: Observation on the clinical efficacy of Shufu in treating children with cold and fever.
[0031] Children's thermoregulatory center is immature, and their ability to regulate body temperature is limited. It is easy to cause benign febrile convulsions, epileptic seizures, tachycardia and many other discomforts. brain damage. In the rat woman treatment group, 90% of these patients' fever symptoms returned to normal body temperature in a relatively short period of time.
[0032] Survey data: number of patients treated: 100, age: 2-15 years old, of which: 20 people aged 2-6 years old, 55 people aged 6-10 years old, 25 people aged 10-15 years old. 65 people took it once, and 35 people took it twice. The effective number of people is 92, and the effect is not obvious for 8 people.
[0033] Case report: Cheng X, 12 years old, had a fever due to a cold, and his body temperature reached 39.0°C. He dried 2 pieces of ratwort. After 4 hours, his body temperature retur...
Embodiment 3
[0034] Example 3: Observation of the clinical efficacy of Shufu in treating adults with cold and fever.
[0035] Survey data: Number of people treated: 30 people, age: 18-40 years old, of which: 15 people aged 18-25 years old, 10 people aged 26-35 years old, 5 people aged 36-40 years old. 25 people took it once, and 5 people took it twice. The effective number of people is 27, and the effect is not obvious for 3 people.
[0036] Case report: Liu ××, 25 years old, had a fever due to a cold, and his body temperature reached 39.4°C. He dried 4 pieces of ratwort. After 4 hours, his body temperature returned to normal, and his headache and other symptoms were alleviated.
[0037] In practical application, murine can be used as a single component, combined with one or more pharmaceutically acceptable carriers or excipients to make a pharmaceutical composition (single prescription), which is used to treat colds caused by colds or caused by bacteria, viruses, etc. Diseases and sympt...
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