On-line artifact removing method synchronizing EEG-fMRI

A technology of artifacts and signals, applied in the field of brain signal processing, to achieve the effect of reducing equipment requirements, meeting data processing speed requirements, and reducing delay

Active Publication Date: 2019-01-18
SOUTH CHINA UNIV OF TECH
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Problems solved by technology

The inventions mentioned above have failed to perform synchronous real-time denois

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  • On-line artifact removing method synchronizing EEG-fMRI

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Embodiment Construction

[0037] The present invention will be further described below in conjunction with specific examples.

[0038] The synchronous EEG-fMRI online artifact removal method provided in this embodiment can be applied to fMRI and EEG hybrid brain-computer interface platforms, including the following steps:

[0039] 1) Design the program framework, the program includes two parts: the signal collected by the recording amplifier and the denoising process of the signal.

[0040] 2) The signal acquisition thread first creates a separate thread for each amplifier channel that needs to be denoised, and is responsible for the parallel processing of each channel signal.

[0041] 3) Perform high-pass filtering on the collected EEG signals to filter out temperature drift and pulse artifacts, design the filter to obtain parameters, and then export the filter parameters to the file of the program framework for use.

[0042] 4) Upsampling the filtered signal in step 3) and synchronizing the EEG sign...

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Abstract

The invention discloses an on-line artifact removing method synchronizing EEG-fMRI. The method comprises the following steps: 1) high-pass filtering of EEG signals; 2) upsampling the filtered signal and synchronizing the EEG signal with the marker emitted by the MRI device; 3) obtain a signal Sr with residual artifacts; 4) residual gradient artifacts are present in the signal Sr, and gradient artifacts template denoising and PCA denoising are constructed to obtain the gradient artifacts canceled signal Sc; 5) ECG is contain in that signal Sc, and a QRS peak of the ECG is detected; 6) clustering the ECG with K-means according to different periods; 7) reintegrate each EEG signal into m-segment EEG signals accord to time sequence, and performing OBS processing on that m-segment EEG signals; 8) according to the time sequence of the original signal, reconstructing EEG signal to obtain EEG signal after removing ECG artifact. The invention can collect EEG signal at the same time of scanning and collecting fMRI image, and real-time remove artifact through denoising algorithm to obtain EEG signal with high signal-to-noise ratio.

Description

technical field [0001] The invention relates to the technical field of brain signal processing, in particular to an online method for removing artifacts of synchronous EEG-fMRI. Background technique [0002] With the development of brain science research, the combination of electroencephalogram signal (EEG) and functional magnetic resonance imaging (fMRI) has attracted extensive attention and research. EEG signals have the characteristics of low spatial resolution and high temporal resolution, while functional magnetic resonance imaging has the characteristics of low temporal resolution and high spatial resolution. Research on the pathogenesis of functional and psychiatric disorders as well as cognition is very important. [0003] In the experiment of synchronous EEG-fMRI acquisition of EEG signals, since the EEG signal (EEG signal) is acquired in the MRI scanning environment, three kinds of artifacts will be introduced in such an experimental environment: [0004] 1. Puls...

Claims

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Application Information

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IPC IPC(8): A61B5/0476
CPCA61B5/7203A61B5/725A61B5/369
Inventor 于承鑫俞祝良顾正晖李远清
Owner SOUTH CHINA UNIV OF TECH
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