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Systems and methods for reducing noise caused by stimulation artifacts in neural signals received by neuro-modulation devices

A neural signal and neuromodulation technology, applied in spinal nerve electrodes, applications, electrotherapy, etc., can solve problems such as attenuation artifacts, unavailable key parts of data, and lack of continuous neural signal recording

Inactive Publication Date: 2019-02-05
RGT UNIV OF CALIFORNIA
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

In particular, assuming that the frequency content of these artifacts is within the desired signal bandwidth of the received neural signal, the artifacts generally cannot be attenuated using simple frequency-selective filtering techniques
Existing solutions (e.g., blanking recording channels during stimulation, self-eliminating stimulating electrodes, etc.) do not overcome all challenges faced in reducing noise from these artifacts
Furthermore, existing solutions lack the ability to perform continuous neural signal recordings during the stimulation phase, making critical parts of the data unusable

Method used

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  • Systems and methods for reducing noise caused by stimulation artifacts in neural signals received by neuro-modulation devices
  • Systems and methods for reducing noise caused by stimulation artifacts in neural signals received by neuro-modulation devices
  • Systems and methods for reducing noise caused by stimulation artifacts in neural signals received by neuro-modulation devices

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Embodiment Construction

[0036] Turning now to the drawings, an energy-efficient implementation of an Adaptive Stimulation Artifact Reduction (ASAR) process capable of adaptively removing stimulation signal artifacts from neural signals in accordance with some embodiments of the present invention is disclosed to alter Stimulating properties at multiple sites. According to several embodiments, a blind artifact template detection technique is utilized, which in combination with the ASAR process can eliminate the need for any prior knowledge of the temporal and structural properties of the stimulation pulses. In addition, processes according to some embodiments of the present invention also effectively deal with non-linear mapping of brain tissue and non-idealities of electrode interfaces through linear filtering. According to many embodiments, the use of blind artifact templates enables the ASAR process to combat uncertainties due to non-idealities in timing, stimulator circuits, and / or sensing circuits...

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Abstract

System and methods that cancel artifacts of stimulation signals from neural signals are disclosed. In several embodiments, the systems and methods determine a threshold value for the neural signal inthe absence of artifacts. The threshold value can then be used to detect an artifact in received neural signals. In a number of embodiments, a template can be used to cancel an artifact from a neuralsignal in response to the neural signal being greater than the threshold value.

Description

[0001] Federal Statement of Support [0002] This invention was made with Government support under N66001-14-24029 awarded by the US Department of Defense / Advanced Research Projects Agency (DARPA). The government has certain rights in this invention. [0003] cross-referenced application [0004] This application claims priority to U.S. Provisional Patent Application No. 62 / 343,777, filed May 31, 2016, entitled "System And Method for Reducing Noise Caused by Stimulation Artifacts in Neural Signals Received By a Neuro-Modulation Device," which The application is hereby incorporated by reference as if set forth herein. technical field [0005] The present invention relates to neuromodulation devices. More particularly, the present invention relates to reducing noise in neural signals received by a neuromodulation device. Still more particularly, the present invention relates to reducing noise introduced into neural signals from analog signals. Background technique [0006...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61B5/00A61B5/04A61N1/00A61N1/05A61N1/08A61N1/18A61N1/36
CPCA61N1/05A61N1/00A61N1/08A61N1/18A61N1/36A61B5/725A61B5/7203A61B5/24A61B5/369A61B5/00A61B5/7217A61B5/7246A61N1/0551A61N1/36125
Inventor D·马可维克A·H·萨耶德S·巴希尔-卡泽鲁尼S·维拉斯基H·萨拉米
Owner RGT UNIV OF CALIFORNIA
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