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A liquid crystal slow release system containing hemp extract or cannabidiol

A technology of cannabidiol and extracts, which is applied in the field of liquid crystal slow-release systems with high concentrations of active substances, can solve the problems of undisclosed liquid crystal slow-release systems and unresolved stimulation effects

Inactive Publication Date: 2019-03-05
HANYI BIO TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the irritating effect of high-concentration active ingredients on the skin has not been solved, and there is no liquid crystal slow-release system containing high-concentration active substances of cannabis extract or cannabidiol

Method used

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  • A liquid crystal slow release system containing hemp extract or cannabidiol
  • A liquid crystal slow release system containing hemp extract or cannabidiol
  • A liquid crystal slow release system containing hemp extract or cannabidiol

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0069] The preparation of embodiment 1 hemp extract

[0070] (1) Wash and air-dry the raw materials (hemp stalk core, cannabis flower, cannabis leaf);

[0071] (2) pulverize the above-mentioned air-dried raw materials, and then pass through a 40-mesh sieve;

[0072] (3) The obtained powder was cold-soaked and extracted twice with 6 times the amount of 45% ethanol, each time for 1.5 hours;

[0073] (4) Combine extracts, decolorize through 0.5wt% activated carbon adsorption;

[0074] (5) Concentrate under reduced pressure to a relative density of 1.02 at a temperature of 70°C to obtain the cannabis extract.

[0075] According to the above preparation method,

[0076] When the raw material is cannabis leaves, the cannabis extract 1A is obtained;

[0077] When the raw material is cannabis flower, the cannabis extract 1B is obtained;

[0078] When the raw material is hemp stalk core, hemp extract 1C is obtained;

[0079] When the raw materials are cannabis leaves and cannabis...

Embodiment 2

[0081] The preparation of embodiment 2 hemp extract

[0082] (1) Use 9 times the amount of ethanol to heat and reflux the raw materials (marijuana leaves, hemp stalks, hemp flowers) for 1 hour;

[0083] (2) remove residue by filtration, and remove solvent under vacuum condition;

[0084] (3) heating the obtained extract at a temperature of about 125° C. for about 40 minutes;

[0085] (4) Carry out chromatographic separation subsequently, wherein mobile phase mixture is made up of ethanol / water and acetic acid, obtains cannabis extract.

[0086] According to the above preparation method,

[0087] When the raw material is cannabis leaves, cannabis extract 2A is obtained;

[0088] When the raw material is cannabis flower, the cannabis extract 2B is obtained;

[0089] When the raw material is hemp stalk core, hemp extract 2C is obtained;

[0090] Cannabis extract 2D is obtained when the raw materials are cannabis leaves and cannabis flowers;

[0091] Wherein the hemp extract...

Embodiment 3

[0092] The preparation of embodiment 3 hemp extract

[0093] (1) Use 7 times the amount of ethanol to heat and reflux the raw materials (cannabis leaves, hemp stalks, hemp flowers) for 1.5 hours;

[0094] (2) filter to remove residue;

[0095] (3) extracting at least twice with 5% aqueous sodium hydroxide solution, wherein the aqueous sodium hydroxide solution contains 20wt% ethanol;

[0096] (4) The extract is mixed with 5% sulfuric acid solution to make the pH value 3;

[0097] (5) Then use aliphatic hydrocarbons to extract twice, and remove the solvent under low-temperature vacuum;

[0098] (6) Carry out chromatographic separation subsequently, wherein mobile phase mixture is made up of ethanol / water and acetic acid, obtains cannabis extract.

[0099] According to the above preparation method,

[0100] When the raw material is cannabis leaves, the cannabis extract 3A is obtained;

[0101] When the raw material is cannabis flower, the cannabis extract 3B is obtained;

...

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Abstract

The invention discloses a liquid crystal slow release system containing hemp extract or cannabidiol for high-concentration active compounds to overcome a defect that release speeds of cosmetics or preparations for external use containing hemp extract or cannabidiol are too high, and a defect that high-concentration active compounds irritate skin. The invention further provides application of the hemp extract or cannabidiol in preparation of cosmetics, with the cosmetics being provided with the liquid crystal slow release system.

Description

technical field [0001] The invention relates to the field of cosmetics, in particular to a liquid crystal slow-release system containing high-concentration active substances of cannabis extract or cannabidiol. Background technique [0002] The transfer of functional ingredients in cosmetics refers to the process in which the active ingredients in cosmetics act on the skin surface or enter the epidermis or dermis, where they accumulate and function. For example, UV absorbers in sunscreen products should stay on the skin surface to absorb and reflect ultraviolet rays; whitening agents in whitening products often act on the basal layer in the epidermis to block the production of melanin; and the efficacy of anti-aging products The ingredients often act on the fibroblasts in the dermis to make the skin elastic. [0003] Studies have shown that skin care products on the market contain a lot of nutrients, but regardless of the type and efficacy of these nutrients, if the skin can...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/02A61K8/34A61Q19/00
CPCA61K8/0295A61K8/347A61K8/97A61K2800/10A61Q19/00
Inventor 于朝晖张可谭昕吴亚南李萌
Owner HANYI BIO TECH CO LTD
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