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Application of lactobacillus paracasei N1115 to prevention of colitis, corresponding baby milk powder and application

A technology of infant milk powder and lactobacillus, applied in the field of bioengineering, can solve problems such as poor effect, no clear and effective methods and means, and unclear mechanism, so as to achieve the effect of ensuring good health, rich nutrition and reasonable formula

Inactive Publication Date: 2019-03-19
JUNLEBAO DAIRY GRP CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, because the mechanism of IBD is not clear, there are no clear and effective methods and means for the prevention of IBD in the prior art. At present, traditional Chinese medicine or combined traditional Chinese and Western medicine are generally used in China, but the effect is not good.

Method used

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  • Application of lactobacillus paracasei N1115 to prevention of colitis, corresponding baby milk powder and application
  • Application of lactobacillus paracasei N1115 to prevention of colitis, corresponding baby milk powder and application
  • Application of lactobacillus paracasei N1115 to prevention of colitis, corresponding baby milk powder and application

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0031] Example 1 The application of Lactobacillus paracasei N1115 to prevent colitis

[0032] In this embodiment, newborn C57BL / 6 mice were used as test subjects. The mice used were 12 female and 12 male mice provided by Vanderbilt University in the United States, with a body weight of 1.5 g, including the following steps:

[0033] Step 1. Intervention: 24 newborn C57BL / 6 mice were randomly divided into two groups of 6 females and 6 males each, one group was the Lactobacillus paracasei N1115 intervention group, and the other group was the control group. Among them, the mice in the Lactobacillus paracasei N1115 intervention group were fed with 10 bacteria of Lactobacillus paracasei N1115 every day from the first day after birth to the seventh day after birth. 7 CFU (20μl water contains 10 bacteria 7 CFU); from the 8th day to the 14th day after birth, the mice were fed with 10 bacteria of Lactobacillus paracasei N1115 every day 8 CFU (20μl water contains 10 bacteria 8 CFU). ...

Embodiment 2-7

[0051] Embodiment 2-7 utilizes the infant milk powder prepared by Lactobacillus paracasei N1115

[0052] Examples 2-7 are respectively a kind of infant milk powder prepared by utilizing Lactobacillus paracasei N1115. Their raw material proportioning sees the following table 1:

[0053] The raw material ratio of table 1 embodiment 2-7

[0054]

[0055] The infant milk powder of the corresponding embodiment is obtained by uniformly mixing each raw material component. The probiotic powders in the above table that can prevent colitis are made by mixing curcumin, fructooligosaccharides, high-fat cocoa powder and Lactobacillus paracasei, and their raw material ratios are shown in Table 2 below:

[0056] Probiotic powder raw material ratio in table 2 embodiment 2-7

[0057]

Embodiment 8

[0058] Embodiment 8 The application of infant milk powder provided by Embodiment 2-7

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Abstract

The invention provides an application of lactobacillus paracasei N1115 to prevention of colitis, corresponding baby milk powder and an application. The lactobacillus paracasei N1115 is used for earlyintervention or prevention of the colitis. The baby milk powder prepared through the lactobacillus paracasei N1115 can effectively prevent the colitis, and besides, is reasonable in formula and rich in nutrients. The baby milk powder is suitable for all babies of 0-3 years old.

Description

technical field [0001] The invention belongs to the field of bioengineering, and relates to an application of preventing colitis strains, specifically an application of Lactobacillus paracasei N1115 for preventing colitis; the invention also provides a preparation of Lactobacillus paracasei N1115 A kind of milk powder for infants and young children and its application. Background technique [0002] Inflammatory bowel disease (IBD) is a group of chronic, non-specific intestinal inflammatory diseases of unknown etiology, mainly including ulcerative colitis and Crohn's disease. If the patient suffers from this disease and the symptoms cannot be effectively controlled, inflammation The substance will flow to the whole body with the blood, which may cause systemic immune diseases such as iritis, arthritis, erythema nodosum, etc. Therefore, IBD patients are more likely to suffer from colorectal cancer than ordinary people. [0003] Since the initial symptoms of IBD patients are q...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A23C9/152A23C9/156A23C9/158A23C9/16A23C9/123A61K35/747A61P1/00
CPCA23C9/1234A23C9/152A23C9/1522A23C9/1526A23C9/1528A23C9/156A23C9/158A23C9/1585A23C9/16A61K35/747A61P1/00
Inventor 张栋王世杰朱宏陈建行薛玉玲荀一萍冯丽莉魏立华
Owner JUNLEBAO DAIRY GRP CO LTD
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