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Treating fluid for liquid-based cytology experiments

A technology of cytology and treatment liquid, which is applied in the field of treatment liquid in liquid-based cytology experiments, can solve the problems that restrict the promotion and application of technology, and achieve the effects of easy promotion, complete form and structure, and simple use

Inactive Publication Date: 2019-03-19
武汉宏强医疗器械有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Therefore, the existing technical problems have seriously restricted the popularization and application of the above-mentioned technologies.

Method used

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Examples

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Effect test

Embodiment 1

[0024] Example 1, the preparation method of the treatment solution of the present invention is: 0.41% sodium chloride, 0.04% potassium chloride, 0.04% dodecyltrimethylammonium chloride, 20mM phosphate buffer (pH 7.0), ethanol 26 %, ethylene glycol 6%, sodium citrate 6mM, ethylenediaminetetraacetic acid 3g / L, let the above components be evenly stirred and dissolved.

[0025] The treatment solution prepared in the above examples reduces the cost of use during use, truly and effectively protects the integrity and fixity of cells, avoids cell lysis and swelling, and effectively removes tissue fragments and mucus that have no diagnostic value in the sample. Impurities such as clumps and red blood cells are easy to promote and save time for sample preparation.

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PUM

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Abstract

The invention provides a treating fluid for liquid-based cytology experiments. The treating fluid comprises sodium chloride, potassium chloride, dodecyl trimethyl ammonium chloride, ethyl alcohol, glycol, sodium citrate, phosphate buffer and edetic acid. Use cost is reduced, integrity and immobility of cells are protected, cell lysis and expansion are avoided, impurities such as tissue fragments,mucus block masses and red blood cells without diagnostic values in samples are effectively removed, the treating fluid is easy to popularize, and sample preparation time is saved.

Description

technical field [0001] The invention relates to the technical field of biological preparations; in particular, it relates to a treatment solution for liquid-based cytology experiments. Background technique [0002] Thin-layer cell preparation technology is an integral part of pathological diagnosis, and the quality of preparation technology directly affects whether pathologists can make correct pathological diagnosis. [0003] The third-generation cytology production technology—liquid-based sedimentation production, entered the Chinese market at the end of 2001. Compared with the traditional Pap smear examination, it significantly improved the satisfaction of specimens and the detection rate of abnormal cells, and solved the problem. Traditional smears have high false negative rate, high rate of lost cells, poor smear quality, excessive mucus, blood or inflammatory cells and other technical problems, which have made a significant contribution to the diagnosis of exfoliated c...

Claims

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Application Information

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IPC IPC(8): G01N1/28
CPCG01N1/2813
Inventor 不公告发明人
Owner 武汉宏强医疗器械有限公司
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