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Application of Fragrant Green Orchid Extract in the Preparation of Medicines for Lowering Uric Acid

A technology for lowering uric acid and fragrant green blue, which is applied in the direction of drug combination, pharmaceutical formula, plant raw materials, etc., to achieve the effect of enriching clinical indications and meeting the needs of clinical medication

Active Publication Date: 2022-01-28
WUHAN JIANMIN ZHONGWEI PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] However, there are still few relevant literature reports on the use of fenugreek or its extracts for lowering uric acid or treating other metabolic diseases such as gout.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0018] Take the Chinese herbal medicine, decoct and extract twice with water, each time for 2 hours, collect the extract, concentrate, dry, and pulverize into fine powder to obtain the water extract of Chinese orchid.

Embodiment 2

[0020] The medicinal material Cinnamomum chinensis is taken, refluxed and extracted twice with 70% (volume) ethanol, each time for 2 hours, the extract is collected, concentrated, dried, and pulverized into fine powder to obtain the ethanol extract of Cinnamomum vulgaris.

Embodiment 3

[0022] Take the fragrant green orchid medicinal material, add water to decoct and extract twice, each time for 2 hours, collect the extract, concentrate it into a clear paste with a relative density of 1.20, and then extract it with saturated n-butanol, ethyl acetate, and petroleum ether respectively, and collect the organic layer, recover the organic solvent and concentrate, dry and pulverize into fine powder. The n-butanol extraction fraction, the ethyl acetate extraction fraction and the petroleum ether extraction fraction of the water extract of the orchid are obtained respectively.

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PUM

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Abstract

The invention discloses a new application of the extract of fenugreek in the preparation of uric acid-lowering medicine, and the invention also discloses a uric acid-lowering medicament, the active ingredient of which is the extract of xiangqinglan. Through the preparation of animal models of hyperuricemia, the effect of the extract of Xiangqinglan on the serum uric acid content of experimental animals was investigated. It was found that all kinds of extracts have a certain effect on reducing uric acid. Therefore, the extract of Xiangqinglan can reduce uric acid. The method can generate or promote uric acid excretion, can be used to prepare uric acid-lowering drugs, and has broad application prospects for treating various diseases caused by high blood uric acid, especially gout.

Description

technical field [0001] The present invention relates to the new application of the extract of fenugreek orchid, especially the new application in the preparation of uric acid-lowering medicine, and belongs to the field of pharmacy. Background technique [0002] Uric acid is the final product of the metabolism of purine substances in the body. The stable level of uric acid in the body involves the balance between the generation, absorption, metabolism and decomposition of uric acid. Once the uric acid metabolism is disturbed, hyperuricemia or a series of symptoms will be induced. Other diseases such as gouty arthritis and hyperuricemia nephropathy. [0003] The current uric acid-lowering drugs mainly include probenecid, benzomarone, and allopurinol, among which allopurinol is a xanthine oxidase inhibitor widely used in clinical practice, which can inhibit the production of uric acid by inhibiting xanthine oxidase , but it can cause liver damage, hypersensitivity allergic syn...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/53A61P19/06
CPCA61P19/06A61K36/53
Inventor 胡准李心愿
Owner WUHAN JIANMIN ZHONGWEI PHARMA CO LTD
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