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Systems, apparatus, and methods for delivery of therapeutic substance to the middle and/or inner ear

A kind of material and tympanic technology, which can be applied in the direction of ear treatment, medical equipment, and equipment introduced into the body, etc., and can solve the problems of easy inflammation and dysfunction of Eustachian tube

Inactive Publication Date: 2019-04-02
TUSKER MEDICAL
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] By connecting the tympanic cavity to the nasopharynx, the Eustachian tube helps to equalize middle ear pressure and drain fluid from the middle ear; however, the Eustachian tube is prone to inflammation and dysfunction

Method used

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  • Systems, apparatus, and methods for delivery of therapeutic substance to the middle and/or inner ear
  • Systems, apparatus, and methods for delivery of therapeutic substance to the middle and/or inner ear
  • Systems, apparatus, and methods for delivery of therapeutic substance to the middle and/or inner ear

Examples

Experimental program
Comparison scheme
Effect test

example 1

[0064] Example 1: A system for delivering a therapeutic substance to at least one of a tympanic cavity or an inner ear of a subject, the system comprising: a reservoir configured to contain a therapeutic substance; an outlet configured to The therapeutic substance is configured to deliver the therapeutic substance from the reservoir to at least one of: the lumen of a tympanostomy tube disposed in the tympanic membrane bordering the tympanic cavity; the tympanic cavity; and the round window of the inner ear bordering the tympanic cavity such that the therapeutic substance Deliverable to at least one of the tympanic cavity and the inner ear.

example 2

[0065] Example 2: The system of example 1, wherein the outlet comprises at least one of a conduit or a core.

example 3

[0066] Example 3: The system of any of Examples 1 and 2, further comprising a tympanostomy tube, and wherein the outlet is integral with the tympanostomy tube.

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PUM

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Abstract

Systems (300), apparatus, and methods are described for delivering a therapeutic substance to an ear of a subject, including a reservoir (300) configured to contain the therapeutic substance and an outlet (320) configured to transport the therapeutic substance from the reservoir to a lumen of a tympanostomy tube disposed within a tympanic membrane bordering the tympanic cavity and / or the tympaniccavity via the lumen of the tympanostomy tube, such that the therapeutic substance can be delivered to the tympanic cavity and / or a round window to an inner ear bordering the tympanic cavity.

Description

[0001] Cross References to Related Applications [0002] This application claims priority to pending U.S. Provisional Patent Application No. 62 / 371,583, filed August 5, 2016, entitled "Systems, Apparatus, and Methods for Delivering Therapeutic Substances to Middle and / or Inner Ears" , the disclosure of which is incorporated herein by reference. technical field [0003] The present disclosure generally relates to systems, devices, and methods for delivering substances to the ear of a subject. More specifically, the present disclosure relates to systems, devices, and methods for accessing and delivering therapeutic substances to the tympanic cavity or middle and / or inner ear of a subject. Background technique [0004] In humans and many other animals, the tympanum is a small cavity in the stony temporal bone. Such as figure 1 As shown in , the tympanic cavity surrounds the bones of the middle ear (including the malleus, incus, and stapes) and is bounded by six walls. The...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61F11/00
CPCA61L27/54A61F2250/0067A61F2250/0068A61L2430/14A61M5/1428A61M5/141A61K31/00A61F11/202A61M31/002A61M2205/04A61M2210/0668
Inventor E·戈德法布R·吉罗特拉A·阿博法思
Owner TUSKER MEDICAL
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