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Medical cold-compress gel for improving gout and preparation method and application thereof

A technology for gout and gel is applied in the preparation of medical cold compress gel, the medical cold compress gel for improving gout, and the application field of medical cold compress gel, which can solve the problems of treating the symptoms but not the root cause, drug dependence, and low concentration of active ingredients. , to achieve the effect of relieving redness, swelling, heat and pain, improving the effect and high effective treatment rate

Inactive Publication Date: 2019-05-03
曲沃李时珍医药科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] In order to overcome the deficiencies of the prior art, one of the objectives of the present invention is to provide a medical cold compress gel for improving gout, so as to solve the problems of existing Western medicines for improving sensitive skin problems, such as high recurrence rate and easy drug dependence. It can also effectively avoid problems such as low concentration of active ingredients in traditional Chinese medicine, long time to improve skin sensitivity symptoms, poor effect, and difficulty in achieving symptom relief with short-term medication.
[0006] The second object of the present invention is to provide a method for preparing a gout-improving medical cold compress gel. The gout-improving medical cold compress gel prepared by this method can overcome the existence of existing Western medicines used to improve sensitive skin problems. It can also effectively avoid the defects of low concentration of active ingredients, long time to improve skin sensitivity symptoms, and poor effect in corresponding traditional Chinese medicines.

Method used

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  • Medical cold-compress gel for improving gout and preparation method and application thereof
  • Medical cold-compress gel for improving gout and preparation method and application thereof
  • Medical cold-compress gel for improving gout and preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0037]Preparation steps: Weigh 3g of sun-dried Salvia miltiorrhiza, 10g of Qingfengteng, 20g of Epimedium, 4g of Chuanqiong, 1g of Shengdi and 2g of Cynomorium to form component A. Weigh 12g of sun-dried safflower, 10g of taro, 5g of Aconitum aconitifolia, 15g of rosin, 4g of scorpion, 24g of bark of Vitex chinensis and 6g of licorice to form component B.

[0038] Preparation of the first extract step: Component A is transferred to a round-bottomed flask, according to the ratio of material to liquid (i.e. the ratio of mass to volume) is 1:5, to add mass fraction to the round-bottomed flask is 95% ethanol, will stir The rod was placed in a round bottom flask and stirred for 80 min (or the round bottom flask was shaken on a shaker for a corresponding time). Connect the round-bottom flask to a condensing reflux pipeline to prepare a set of reflux extraction device, place the round-bottom flask in a constant temperature water bath at 85°C, and rotate the round-bottom flask for ref...

Embodiment 2

[0042] Preparation steps: Weigh 10g of sun-dried Salvia miltiorrhiza, 8g of Qingfengteng, 10g of Epimedium, 12g of Chuanqiong, 3g of Shengdi and 6g of Cynomorium to form component A. Component B was composed of 9g of sun-dried safflower, 5g of taro, 16g of Aconitum aconitifolia, 6g of rosin, 9g of scorpion, 12g of safflower bark and 12g of licorice.

[0043] Preparation of the first extract step: Component A is transferred to a round bottom flask, and according to the ratio of material to liquid (i.e. the ratio of mass to volume) is 1:8, adding mass fraction to the round bottom flask is 90% ethanol, stirring The rod was placed in a round bottom flask and stirred for 65 min (or the round bottom flask was shaken on a shaker for the corresponding time). Connect the round-bottom flask to a condensing reflux pipeline to prepare a set of reflux extraction device, place the round-bottom flask in a constant temperature water bath at 82°C, and rotate the round-bottom flask for reflux e...

Embodiment 3

[0047] Preparation steps: Weigh 7g of sun-dried Salvia miltiorrhiza, 6g of Qingfengteng, 13g of Epimedium, 9g of Chuanqiong, 5g of Shengdi and 5g of Cynomorium to form component A. Component B was composed of 7g of sun-dried safflower, 7g of taro, 12g of Aconitum aconitifolia, 9g of rosin, 12g of scorpion, 16g of bark of Vitex chinensis and 11g of licorice.

[0048] Preparation of the first extract step: transfer component A to a round bottom flask, according to the ratio of material to liquid (i.e. the ratio of mass to volume) is 1:10, add mass fraction to the round bottom flask is 80% ethanol, stir The rod was placed in a round bottom flask and stirred for 50 min (or the round bottom flask was shaken on a shaker for a corresponding time). Connect the round-bottom flask to the condensing reflux pipeline to prepare a set of reflux extraction device, place the round-bottom flask in a constant temperature water bath at 78°C, and rotate the round-bottom flask for reflux extractio...

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Abstract

The invention discloses a medical cold-compress gel for improving gout, which comprises an active extract, carbomer and a hydrogel; the active extract is extracts of salvia miltiorrhiza, caulis sinomenii, Epimedium, Ligusticum chuanxiong Hort, root of rehmannia, cynomorium songaricum, safflower, taro, prepared kusnezoff monkshood root, rosin, scorpion, golden larch bark and licorice; the weight ratio of the active extract, carbomer to hydrogel is 10:1 to 5:10 to 50. The invention also discloses a preparation method of the medical cold-compress gel for improving gout. The medical cold-compressgel for improving gout of the invention adopts a traditional Chinese medicine extract as an active ingredient, and has no toxicity and side effects during the treatment process. By means of the endothermic effect of the cold-compress gel, the cold-compress gel can quickly absorb the burning sensation on the surface of the skin, brings a cool and comfortable feeling to the patient, and effectivelyalleviates the redness and heat pain caused by inflammation.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine skin care products, in particular to a medical cold compress gel for improving gout, and the invention also relates to a preparation method of the medical cold compress gel for improving gout and the application of the medical cold compress gel for improving gout . Background technique [0002] Gout is a characteristic joint inflammation caused by the disorder of purine metabolism and the increase of blood uric acid, which leads to the deposition of uric acid crystals in the joints and the tissues around the joints. Clinically, it is characterized by hyperuricemia, recurrent episodes of characteristic acute arthritis, and gout stone formation. In severe cases, it can cause joint deformity and dysfunction, acute obstructive nephropathy or gouty nephropathy. At present, the prevalence of gout in my country is 0.84% ​​in the general population, about 12 million people, 95% of wh...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/888A61K47/10A61P19/06A61K9/06A61K35/646
Inventor 刘小俊
Owner 曲沃李时珍医药科技有限公司
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