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Scalp care solution and preparation method thereof

A scalp care and sebum technology, applied in skin care preparations, hair care, skin diseases and other directions, can solve problems such as complex preparation methods, and achieve good clinical efficacy, reduced irritation, no irritation and no adverse reactions.

Active Publication Date: 2019-05-14
中国人民解放军陆军特色医学中心
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Patent CN 105106108 B proposes a novel supramolecular controlled slow-release salicylic acid preparation method, first dissolving 1 part of salicylic acid in 10-12 parts of 95% ethanol and 25-32 parts of 1,2-propanediol In the mixed liquid, the salicylic acid alcohol solution, the starch nanocrystalline poloxamer suspension, the α-cyclodextrin aqueous solution, the low molecular weight fish collagen aqueous solution, and the trehalose aqueous solution are mixed to prepare the controlled and sustained release supramolecular salicylic acid Gel, the preparation method is more complicated

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0037] A preparation method of scalp care solution:

[0038] Take 90ml of water, add 6.5g of poloxamer 407, stir to dissolve, then add 1.3g of salicylic acid, mix and heat to 75°C, stir until completely dissolved; cool down to 50°C, add 0.1g of menthol, stir until completely dissolved; cool down After reaching room temperature (20-25°C), add 1.3g of nicotinamide, 1g of dextran, 0.2g of water-soluble ceramide, 0.4g of gypenoside and 0.2g of rosmarinic acid, and stir until completely dissolved; use citric acid / arginine Adjust the pH to pH 5.5-6.5 with acid.

[0039] The ratio of poloxamer to salicylic acid is 2.5-10:1 to ensure that the poloxamer completely dissolves salicylic acid in the scalp care solution. The optimal ratio is 4-6:1, the optimal ratio It is 5:1.

[0040] The preparation method and raw materials are obtained through multiple tests. The ratio of poloxamer and salicylic acid ensures that the poloxamer completely dissolves the salicylic acid in the scalp care s...

Embodiment 2

[0042] A preparation method of scalp care solution:

[0043]Take 450ml of water, add 42.5g of poloxamer 407, stir to dissolve, then add 9g of salicylic acid, mix and heat to 75°C, stir until completely dissolved; cool down to 50°C, add 0.5g of menthol, stir until completely dissolved; then cool down After reaching room temperature (20-25°C), add 5g of zinc gluconate, 1g of allantoin, 1g of dipotassium glycyrrhizinate and 2.5g of witch hazel extract, stir until completely dissolved; adjust the pH to pH 5.5-6.5 with citric acid That's it.

Embodiment 3

[0045] A preparation method of scalp care solution:

[0046] Take 450ml of water, add 40g of Poloxamer 188, stir to dissolve, then add 10g of salicylic acid, mix and heat to 80°C, stir until completely dissolved; cool down to room temperature (20-25°C), then add 4g of zinc gluconate, 4g of allantoin , 4.5g dipotassium glycyrrhizinate and 4.5g witch hazel extract, stir until completely dissolved; use triethanolamine to adjust the pH to pH 5-6.5.

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PUM

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Abstract

The invention relates to a scalp care solution. The scalp care solution comprises, by weight, 1-2% of salicylic acid, 5-10% of a slow-release dispersant, 1-3.5% of a sebum conditioner, 0.5-2% of a repairing agent, 1% of a plant extract and the balance water; preferably, a suitable quantity of a cooling agent such as menthol can be added. The scalp care solution does not contain an alcohol reagent,reduces scalp stimulation and further repairs the skin barrier; by proportioning the content of the components, a synergistic effect of the components is fully exerted, a patient feels comfortable during use and has no stimulation and adverse reactions, and the clinical curative effect is good.

Description

technical field [0001] The invention belongs to the technical field of daily chemical products, and relates to a scalp care solution and a preparation method thereof. Background technique [0002] Greasy hair, itchy scalp, and even severe dandruff are problems encountered by many people. Some of them have strong oil secretion physiologically, and some of them suffer from folliculitis, seborrheic dermatitis or even scalp psoriasis. With the popularization of diagnosis and treatment and the increase of life pressure, the incidence of diseases prone to scalp such as seborrheic dermatitis and scalp psoriasis is increasing day by day. Seborrheic dermatitis and dandruff are common chronic relapsing diseases in dermatology. They are both characterized by skin desquamation and itching. The histological changes are also similar, that is, the hyperproliferation of the epidermis under the stimulation of inflammation and the disorder of the epidermal structure. Unlike seborrheic dermat...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/9789A61K8/86A61K8/73A61K8/68A61K8/67A61K8/63A61K8/49A61K8/37A61K8/368A61K8/27A61K8/34A61K8/365A61P17/04A61P17/08A61Q5/12A61Q19/00
Inventor 罗杰夫雷霞谢广威陈劲奕
Owner 中国人民解放军陆军特色医学中心
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