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analog simulation method for predicting the particle balance interval of a multi-particle chain based on an IB-LB method

A multi-particle and granular technology, applied in special data processing applications, instruments, electrical digital data processing, etc.

Active Publication Date: 2019-05-24
SHANGHAI JIAO TONG UNIV
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AI Technical Summary

Problems solved by technology

At present, most researchers focus on the study of the flow field of single particles and the simulation of particle migration paths, or the arrangement analysis of multi-particle groups, and there are few discussions on the specific particle arrangement and spacing between single particle chains. , which happens to be the key information for particle separation in microfluidic chips

Method used

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  • analog simulation method for predicting the particle balance interval of a multi-particle chain based on an IB-LB method
  • analog simulation method for predicting the particle balance interval of a multi-particle chain based on an IB-LB method
  • analog simulation method for predicting the particle balance interval of a multi-particle chain based on an IB-LB method

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Embodiment Construction

[0033] Such as figure 1 As shown, this implementation example uses the IB-LB method to achieve accurate fluid-solid coupling, thereby accurately simulating the law of fluid flow and the law of multi-particle motion.

[0034] Such as figure 2 Shown is the schematic diagram of the immersed boundary method used in the simulation method. The immersed boundary method separates the fluid from the solid, and the fluid is represented by an Euler grid, which is the dotted line in the figure. The solid is represented by Lagrangian grid points, and the black curve in the figure represents the boundary of the solid. In this way, the delta function is used to exchange information between the Euler grid point and the Lagrangian grid point.

[0035] Such as image 3 Shown is the model D3Q19 adopted by lattice Boltzmann, that is, each lattice point has 19 migration directions on the three-dimensional scale.

[0036] Such as Figure 4 , Figure 5 with Image 6As shown, it shows all po...

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Abstract

An analog simulation method for predicting the particle balance interval of a multi-particle chain based on an IB-LB method is provided. According to the analog simulation method, information betweenfluid solids is accurately transmitted through an immersion boundary method, and accurate description of solid flowing is achieved. Different working conditions are constructed by adjusting model parameters, then the particle distribution condition in micro-scale flow under different working conditions is simulated, namely the axial and longitudinal key distribution positions and the particle spacing are simulated, and then the separation position and the separation frequency are given to control and split charging of particles. According to the invention, the target object can be accurately and efficiently sorted from the to-be-monitored sample for accurate guidance and prediction.

Description

technical field [0001] The present invention relates to a technology in the field of fluid mechanics, in particular to a simulation method for predicting the inter-chain spacing of flow-stabilized particles based on the IB-LB (Immersed Boundary-Lattice Boltzmann) method. Background technique [0002] Microfluidic chip technology can realize the integrated process of particle arrangement, enrichment, screening, separation, and capture at the microscale. It has made great progress in recent years, and its development has opened a new chapter in many fields such as biology, chemistry, and medicine. For example, point-of-care test analyzers (POCT) for clinical diagnosis and treatment can detect various physiological and pathological parameters of patients in real time, providing important assistance for disease diagnosis and condition detection. For example, the water quality detection microsystem based on MEMS technology plays an important role in water pollution control. The ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G06F17/50
Inventor 王珊潘振海
Owner SHANGHAI JIAO TONG UNIV
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