Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Use of rutin naringin as an adjuvant in promoting and maintaining oral tolerance

A naringin ruta and tolerance technology, applied in the field of naringin ruta, can solve problems such as affecting the quality of life of allergic children, food allergy in infants and young children, etc.

Active Publication Date: 2020-02-07
JILIN UNIV
View PDF1 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, eggs contain a variety of allergens, which induce food allergy in infants and young children, and seriously affect the quality of life of allergic children

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Use of rutin naringin as an adjuvant in promoting and maintaining oral tolerance
  • Use of rutin naringin as an adjuvant in promoting and maintaining oral tolerance
  • Use of rutin naringin as an adjuvant in promoting and maintaining oral tolerance

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0032] see Figure 1-18 As shown, the following experimental methods prove that rutin naringin has an auxiliary effect on promoting and maintaining oral tolerance. The specific experimental steps and analysis of mice are as follows:

[0033] laboratory apparatus:

[0034] PHSJ-4A laboratory pH meter Shanghai Lei Magnetic micro oscillator Jiangsu Xinkang Medical Devices Vortex mixer Beijing Dingguochangsheng Biotechnology Microplate reader American BioTek Instruments High speed refrigerated centrifuge American Thermo Fisher -80℃ ultra-low temperature refrigerator Qingdao Haier

[0035] Experimental reagents:

[0036] Mouse IgEELISA Kit American eBioscience Mouse IgG1ELISA Kit American eBioscience Mouse MCP-1ELISA Kit American eBioscience Mouse IgAELISA Kit American eBioscience Chicken Ovalbumin (OVA) American Sigma aluminum adjuvant American Thermo 0.9% sodium chloride soluti...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The present invention relates to the application of narirutin, especially to application of narirutin taken as adjuvant in promotion and maintenance of oral tolerance. The experiment shows that: the narirutin is added into food as an adjuvant to relieve the decreasing of the weight and the body temperature caused by OVA (Ovomucoid) allergy, relieve the diarrhea caused by allergy and relieve the hypersensitivity mediated by various immune globulins so as to have an assistant effect on oral tolerance and promote and maintain the oral tolerance capacity. The application of narirutin taken as adjuvant in promotion and maintenance of oral tolerance has important guidance meaning and referential significance for development of hypoallergenic egg products or other high-protein products and has important inspiration for research of nutrition and health of allergy sufferers.

Description

technical field [0001] The present invention relates to the application of rutin naringin, in particular to the application of rutin naringin added to foods as an adjuvant in promoting and maintaining oral tolerance. Background technique [0002] WO 01 / 89541 (Compagnie Gervais Danone) discloses that the use of Lactobacillus casei in oral compositions increases immunity specific to pathogenic microorganisms. It is especially intended for pathogens affecting the respiratory system, while the composition can be a food or a food supplement. [0003] Patent CN1662154A discloses that probiotics such as Lactobacillus paracasei (lactobacillus paracasei) strains can promote the induction of oral tolerance, and are particularly suitable for promoting oral tolerance to milk protein. However, the microorganisms added to the food are preferably living organisms, which means that such foods need to be transported and sold at low temperature. If the storage conditions are improper, the pr...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Patents(China)
IPC IPC(8): G01N33/543
Inventor 时晓磊赵丽娜杨彬牛丽艳隗继浩
Owner JILIN UNIV
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com