Eimeria tenella SO7-IL-2 protein and preparation method thereof

A technology of SO7-IL-2 and Eimeria, which is applied in the field of genetic engineering, can solve the problems of drug-resistant insect strains, decreased egg production rate, and harm to the chicken industry, so as to reduce the degree of disease and achieve good results. strong protective effect
CN110256576APending Publication Date: 2019-09-20JILIN UNIV
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Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
JILIN UNIV
Publication Date
2019-09-20

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Abstract

The invention provides Eimeria tenella SO7-IL-2 protein and a preparation method thereof. The Eimeria tenella SO7-IL-2 protein based a Pichia pastoris vector is novel Eimeria tenella recombinant yeast protein. Chickens are immunized by protein obtained by recombinant yeast protein total crushing and induction expression, and the recombinant protein extracted by the total crushing method is high in protecting effect. By detecting humoral immunity and cellular immunity level, the results show that the immunity level of the chickens immunized by the protein obtained by recombinant yeast protein total crushing and induction expression is evidently higher than that of control, and the protein can be used for preventing Eimeria tenella diseases.
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Description

technical field

[0001] The invention provides an Eimeria tenella SO7-IL-2 protein and a preparation method thereof, which is based on the Eimeria tenella SO7-IL-2 protein carried by Pichia pastoris, and is a new type of Eimeria tenella SO7-IL-2 protein. The recombined yeast protein of coccidia mesa is used for the prevention of coccidiosis lentilis and belongs to the technical field of genetic engineering. Background technique

[0002] Eimeria tenella is an important parasite of chickens. Apicomplexan parasites in the cells mainly parasitize in the cecum of chickens, which can cause weight loss, serious intestinal lesions and death of chickens, and seriously harm Development of the poultry industry. The disease occurs in chicks aged 15-50 days, the incidence rate is as high as 50%-70%, and the mortality rate is about 20%-30%. Estimates of the annual global economic loss from Eimeria tenaea are approximately US$ 3 billion. Because the disease can cause the growth and devel...

Claims

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