Tumor Microsphere Profile Detection Method and Device
A contour detection and tumor technology, which is applied in the field of tumor microsphere contour detection, can solve the problems of low tumor microsphere size accuracy and tumor microsphere edge contour accuracy, and achieve high accuracy
Active Publication Date: 2020-12-25
江苏艾玮得生物科技有限公司
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[0005] The present invention provides a method and device for detecting the contour of tumor microspheres to solve the problem that the accuracy of the edge contour of tumor microspheres obtained by the prior art is low, resulting in the accuracy of the size of tumor microspheres calculated according to the edge contour. low rate problem
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[0024] It can be seen from the background technology that in the prior art, experimenters usually take images of tumor microspheres according to the culture time, then outline the edge contours of tumor microspheres in the obtained images, and finally use measuring tools to measure the diameter of the obtained edge contours, And the area of the tumor microsphere is calculated according to the diameter. In this process, the edge contour of the tumor microspheres is drawn manually, and the accuracy rate is low, resulting in a low accuracy rate of the size of the tumor microspheres calculated according to the edge contour. In order to solve this problem, an embodiment of the present invention provides a method and device for detecting the contour of tumor microspheres.
[0025] The method and device for detecting the contour of tumor microspheres provided by the embodiments of the present invention will be described in detail below with reference to the accompanying drawings. ...
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The invention discloses a tumor microsphere contour detection method and device. The contour detection method comprises the following steps: acquiring a first contour curve of a tumor microsphere image by using a first edge detection operator; generating a first edge feature; and if each first edge feature is greater than a corresponding preset threshold, determining the first contour curve as anactual contour curve of the tumor microsphere image. The actual contour curve of the tumor microsphere image obtained by using the contour detection method is obtained by using the first edge detection operator, and the correctness of the actual contour curve is determined by using the first edge feature, so that the accuracy is higher, and a calculation result with higher accuracy can be obtainedby subsequently calculating the size of the tumor microsphere by using the actual contour curve.
Description
technical field [0001] The invention relates to the technical field of contour detection, in particular to a method and device for contour detection of tumor microspheres. Background technique [0002] In the three-dimensional cell culture technology of tumor cells, it is necessary to study the killing effect of compounds on tumor cells according to the growth and invasion of tumor cells. Based on this, in the three-dimensional cell culture process of tumor cells, it is necessary to record the contour and shape of the cultured tumor microspheres and measure the size according to the culture time. The tumor microspheres refer to spheres composed of multiple tumor cells, which can be used The area of the tumor microspheres measures the size of the tumor microspheres. [0003] In the prior art, experimenters usually take images of the tumor microspheres according to the culture time, and then outline the edge contours of the tumor microspheres in the obtained images, and the...
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IPC IPC(8): G06T7/13G06T7/62
CPCG06T2207/10056G06T2207/30096G06T7/13G06T7/62
Inventor 顾忠泽徐俊陈早早孙仕琪曹炜叶欢汪丰葛健军
Owner 江苏艾玮得生物科技有限公司