Bioreactor and method for breeding or cultivating biological material
A technology of bioreactors and biomaterials, applied in photobioreactors, biochemical equipment and methods, bioreactor/fermenter combinations, etc., can solve the problem of limited optical resolution of microscopes, uninterruptible microscopes, limited running time, etc. problems, to achieve the effect of protecting the sterilization area, low production risk and high output
Pending Publication Date: 2019-10-22
SCHOTT AG
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Problems solved by technology
The disadvantage of this microscope system is that the microscope is arranged in the medium to be examined, which limits the operating time due to the required power supply, because for image capture a CCD chip is used for miniaturized image capture as well as for imaging unit
Furthermore, the microscope cannot be interfered with and cannot be replaced, for example during the production process
Due to the use of a CCD chip, the optical resolution of this microscope is limited by the pixel size of the light sensor passing through the chip
Method used
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[0123] In the following detailed description of the preferred exemplary embodiment, identical or identically acting components are identified with the same reference numerals in each case in the figures.
[0124] However, for the sake of clarity, the figures are not drawn to scale.
[0125] For the sake of brevity, in the following the container for receiving the fluid medium containing the biological material is also referred to as the container for receiving the fluid medium or more briefly only as the container.
[0126] When the term fluid medium is used within the scope of the present disclosure, this is based on the fact that more than one fluid component may be present in a bioreactor, such as a carrier fluid, in which a biological material or a precursor of a biological material may be in a carrier fluid However, fluid components of the biological material itself or other liquid culture media may also be present in the carrier fluid. However, when only one carrier flu...
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Abstract
The invention relates to a device for supporting an image capturing device on a bioreactor, a bioreactor with the device for supporting the image capturing device, and a method for breeding or cultivating a biological material. The method uses the device for supporting the image capturing device, particularly a microscope device. The device comprises a window including a transparent element, the transparent element is transparent to electromagnetic radiation; and a holder for the image capturing device, wherein the device for supporting the image capturing device is held at least partially inthe through-opening of a feedthrough of a container for holding fluid media containing the biological material, preferably the window seals the through-opening.
Description
technical field [0001] The invention relates to a device for supporting an image capturing device on a bioreactor and to a bioreactor comprising a device for supporting an image capturing device. Background technique [0002] Methods and devices for the production of biological materials, such as biotechnological production processes involving the cultivation of microorganisms, animal and plant cells, are gaining in importance. Biotechnological production processes include, for example, the cultivation of microorganisms, animal and plant cells. However, important to the progress and control of biotechnological production processes is the monitoring of cell growth and cell viability within bioreactors. This has an impact on the yield and thus on the profitability of the overall process. [0003] Traditionally, to determine cell growth and cell viability, samples were taken from the bioreactor and analyzed outside the bioreactor or analyzed offline. However, this does not p...
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IPC IPC(8): C12M1/36C12M1/34C12M1/00
CPCC12M21/02C12M23/22C12M31/10C12M41/06C12M41/46C12M37/04C12M23/48C12M43/00G01N21/255F16M11/00
Inventor C·奥特R·黑特勒
Owner SCHOTT AG