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Multi-nozzle interference-free switching device suitable for biological 3D printers and biological 3D printing method

A technology of 3D printers and switching devices, which is applied in the direction of biological material sampling methods, biochemical cleaning devices, biochemical equipment and methods, etc., can solve the problem of not being able to well meet the requirements of bionic structures, lack of in-depth research and targeted design , limit the number of bioprinting materials and other issues, achieve high printing effect, improve 3D printing accuracy, and avoid interference

Inactive Publication Date: 2019-11-12
HUAZHONG UNIV OF SCI & TECH +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The basic structure of bio-3D printing equipment currently on the market is basically similar to conventional printing equipment in other fields, which can no longer meet the requirements of tissue engineering for bionic structures at this stage.
[0003] More specifically, the existing bio-3D printing equipment mainly has the following technical defects: First, due to the limitations of the mechanical mechanism itself, mainstream equipment is usually only equipped with a single or double nozzle, which severely limits the bio-printing materials. Second, even if the laboratory independently develops bio-3D printers with more nozzles, the interference between nozzles is likely to occur in this type of equipment, which directly affects the printing accuracy and even causes printing failures; finally, the existing There is still a lack of sufficient in-depth research and targeted design on how to realize multi-layer, multi-material and diverse biomimetic structure 3D printing in equipment

Method used

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  • Multi-nozzle interference-free switching device suitable for biological 3D printers and biological 3D printing method
  • Multi-nozzle interference-free switching device suitable for biological 3D printers and biological 3D printing method

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0045] Example 1: Each layer model is only composed of a single printing material

[0046] Step 1: Configure printing materials

[0047] According to the composition of the model, configure the corresponding printing materials required. In this example, configure 4 copies of the required printing materials, and put them into two 5ml self-made syringes and two 10ml self-made syringes according to the dosage requirements and printing requirements. Syringe barrels, then put two 5ml self-made syringe barrels into two 5ml modular nozzles, and two 10ml self-made syringe barrels into two 10ml modular nozzles, and then put 4 modular nozzles into 4 In a modular nozzle support, both sides are fixed with screws;

[0048] Step 2: Generate print path

[0049] Step A: slice the model in the Z-axis direction according to a certain thickness, each slice of the model is one layer, and then use the control software to generate a path file that can be recognized by the biological 3D printer pr...

example 2

[0053] Example 2: Each layer model is composed of multiple printing materials

[0054] Step 1: Configure printing materials

[0055] According to the composition of the model, configure the corresponding printing materials required. In this example, configure 4 copies of the required printing materials, and put them into two 5ml self-made syringes and two 10ml self-made syringes according to the dosage requirements and printing requirements. Syringe barrels, then put two 5ml self-made syringe barrels into two 5ml modular nozzles, and two 10ml self-made syringe barrels into two 10ml modular nozzles, and then put 4 modular nozzles into 4 In a modular nozzle support, both sides are fixed with screws;

[0056] Step 2: Generate print path

[0057] Step A: slice the model in the Z-axis direction according to a certain thickness, each slice of the model is one layer, and then use the control software to generate a path file that can be recognized by the biological 3D printer printi...

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PUM

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Abstract

The invention belongs to the technical field of biological 3D printing, and discloses a multi-nozzle interference-free switching device suitable for biological 3D printers. The multi-nozzle interference-free switching device suitable for biological 3D printers comprises a back plate, as well as nozzle supports, modular nozzles, two-way ball screws, screw nuts, stepping motors and the like which are arranged on the back plate; 4 or more modular nozzles are installed on the nozzle supports in a detachable way; the screw nuts are installed on the two-way ball screws, and are respectively in fixedconnection with the nozzle supports via nozzle connectors; and the upper ends of the two-way ball screws are respectively connected with the stepping motors via couplings. The invention further discloses a corresponding printing process method. Being applied, the multi-nozzle interference-free switching device suitable for biological 3D printers is capable of better satisfying specific process requirements of biological 3D printing, such as bionic structure and the like; moreover, the device is capable of ensuring that the multiple nozzles do not interfere with each other throughout printingprocess, thereby allowing fine adjustment of z-axis direction with higher precision. Thus, multi-level, multi-material and multi-gradient biological model printing effects can be realized.

Description

technical field [0001] The invention belongs to the technical field related to biological 3D printing, and more specifically relates to a multi-nozzle non-interference switching device and method suitable for biological 3D printers. Background technique [0002] The rapid development of tissue engineering has increasingly put forward higher technical requirements for the performance of biological 3D printing equipment. The basic structure of bio-3D printing equipment currently on the market is basically similar to conventional printing equipment in other fields, which can no longer meet the requirements of tissue engineering for biomimetic structures at this stage. [0003] More specifically, the existing bio-3D printing equipment mainly has the following technical defects: First, due to the limitations of the mechanical mechanism itself, mainstream equipment is usually only equipped with a single or double nozzle, which severely limits the bio-printing materials. Second, e...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C12M1/00B29C67/00B29C64/112B29C64/20B33Y10/00B33Y30/00
CPCB29C64/112B29C64/20B33Y10/00B33Y30/00C12M33/00
Inventor 吴田俊张祥林
Owner HUAZHONG UNIV OF SCI & TECH
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