Uniform Mixing device for reagent tray magnetic beads as well as use method

A reagent disk and mixing technology, which is applied in the field of automatic magnetic particle chemiluminescence immunoassay analyzer equipment, can solve the problems of reduced service life, wear of moving parts of the reagent disk, and low success rate of scanning codes, so as to reduce rotation and shorten experiments Time, the effect of reducing wear

Active Publication Date: 2019-11-15
山东康华生物医疗科技股份有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In the previous design, the magnetic bead mixing large gear was fixed and installed, which required the entire reagent outer disk assembly to rotate back and forth to drive the magnetic bead mixing seat to rotate the mixing magnetic beads. This would cause that if the reagent arm rotated to the required When the sample is added, the outer ring assembly of the reagent tray has not turned to the corresponding position. At this time, the reagent arm must wait for the outer ring assembly of the reagent tray to turn to the correct position, and the reagent arm goes down to add samples, which will cause: 1. Every time the magnetic beads are mixed, the reagent plate needs to be rotated back and forth, and then returned to the reagent loading position, which will cause a long delay in the mixing of the magnetic beads, and will cause the luminometer reagent plate to over-period alarm and terminate the experiment. ;2. It is not conducive to shortening the experiment time of the entire luminometer in the later stage. The highlight of the luminometer is the fast and accurate results; 3. The moving parts of the reagent plate are severely worn and the service life is reduced; The scanning code does not recognize the phenomenon, the magnetic beads are in the middle circle, and the inner circle is blocked by reagent bottles with other components, which will cause the code scanning success rate to be too low

Method used

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  • Uniform Mixing device for reagent tray magnetic beads as well as use method
  • Uniform Mixing device for reagent tray magnetic beads as well as use method
  • Uniform Mixing device for reagent tray magnetic beads as well as use method

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0030] Embodiment 1: as attached Figure 1-13 As shown, a reagent disk magnetic bead mixing device includes an outer disk 1, the bottom of the outer disk 1 is provided with a first gear 2, and the upper part of the outer disk 1 is provided with a plurality of mixing seats 11, and the mixing seats 11 A second gear 12 is connected, and the second gear 12 meshes with the first gear 2 , and the first gear 2 meshes with a third gear 21 , and the third gear 21 is connected with a first driving device 22 . The first driving device 22 drives the third gear 21 to rotate, the third gear 21 drives the first gear 2 to rotate, the first gear 2 drives the mixing seat 11 to rotate, and the mixing seat 11 contains reagents mixed with magnetic beads. When mixing the magnetic beads, you only need to turn on the first driving device, and the mixing seat will rotate independently to mix the magnetic beads.

[0031] Such as Image 6 with Figure 9 As shown, the mixing seat 11 corresponds to the...

Embodiment 2

[0041] Embodiment 2: as Figure 1-13 As shown, open the second driving device 141 and the third driving device 44; the second driving device 141 drives the fifth gear 14 to rotate, the fifth gear 14 drives the fourth gear 13 to rotate, the fourth gear 13 drives the entire outer disk 1 to rotate, and the outer disk 1 rotates to the sample loading position, and at the same time, the inner disk 4 is also rotated to the sample loading position driven by the third driving device 44; the first driving device 22 is turned on, and the first driving device 22 drives the third gear 21 to rotate, and the third gear 21 drives the third gear 21 to rotate. A gear 2 rotates; the first gear 2 drives the second gear 12 meshed with it to rotate; the second gear 12 drives the mixing seat 11 to rotate, and the magnetic beads in the mixing seat 11 realize mixing, and at the same time when the mixing seat 11 rotates , the code scanner 6 scans the reagent barcode in the mixing seat 11; the sample ne...

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PUM

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Abstract

The invention provides a uniform mixing device for reagent tray magnetic beads as well as a use method. The device comprises an outer tray, wherein a first gear is arranged at the bottom of the outertray, a plurality of uniform mixing seats are arranged on the outer tray, second gears are connected with the uniform mixing seats, the second gears are meshed with the first gear, a third gear is meshed with the first gear, and a first driving device is connected with the third gear. The third gear is driven to rotate by the first driving device, the first gear is driven to rotate by the third gear, the uniform mixing seats are driven to rotate by the first gear, and a reagent mixed with magnetic beads is placed in the uniform mixing seats. When the magnetic beads are required to be uniformlymixed, only the first driving device is required to start, and the uniform mixing seats can rotate independently to uniformly mix the magnetic beads. The first gear drives the plurality of the secondgears to simultaneously rotate so as to drive the uniform mixing seats to rotate, the uniform mixing of the magnetic beads can be realized, the outer tray is not required to realize the uniform mixing of the magnetic beads, the experiment time is shortened, the rotation of the outer tray is reduced, so that wear of each component is reduced.

Description

technical field [0001] The invention relates to the technical field of automatic magnetic particle chemiluminescence immunoassay analyzer equipment, in particular to a reagent disk magnetic bead mixing device and a use method. Background technique [0002] Reagent mixing is an important breakthrough in the field of medical detection technology and an important part of the stability of chemiluminescence instruments. The quality of magnetic bead mixing will directly affect the experimental results. In the previous design, the magnetic bead mixing large gear was fixed and installed, which required the entire reagent outer disk assembly to rotate back and forth to drive the magnetic bead mixing seat to rotate the mixing magnetic beads. This would cause that if the reagent arm rotated to the required When the sample is added, the outer ring assembly of the reagent tray has not turned to the corresponding position. At this time, the reagent arm must wait for the outer ring assembl...

Claims

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Application Information

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IPC IPC(8): G01N35/00B01F9/00
CPCG01N35/00G01N35/00732G01N2035/00514B01F29/321B01F2101/23
Inventor 杨帆詹越波安倍莹姚凯伦李大伟葛玮
Owner 山东康华生物医疗科技股份有限公司
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