Brain function network feature classification method

A functional network and feature classification technology, applied in the field of biomedical information, can solve the problems of large time and labor costs, affecting the results of early diagnosis, and omissions in the division of brain regions of interest.

Active Publication Date: 2019-12-20
CHANGZHOU UNIV
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AI Technical Summary

Problems solved by technology

Although this method is effective, it also has disadvantages
First, there may be some human errors, and because the biomarkers of the disease are not clear, there may be omissions in the division of brain regions of interest, which will affect the results of early diagnosis; second, the algorithm model requires a large amount of data for training , but this requires a great deal of time and manpower

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  • Brain function network feature classification method
  • Brain function network feature classification method
  • Brain function network feature classification method

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Embodiment Construction

[0045] In order to deepen the understanding of the present invention, the present invention will be described in further detail below in conjunction with the accompanying drawings and embodiments, which are only used to explain the present invention and do not limit the protection scope of the present invention.

[0046] Such as Figure 1 to Figure 3 As shown, a method for classification of brain functional network features, combined with a deep polynomial network model, includes the following steps:

[0047] (1) First collect the resting-state fMRI images of each subject's brain and perform reading and format conversion. Before the test, it is necessary to understand the physical state of the volunteers, and remind the subjects to stay awake and not have any conscious thinking activities. Use PHILIPS 3.0-Tesla scanner to collect brain fMRI data, convert the read fMRI data into NIFTI format using DICOM format, and then perform preprocessing such as time correction, head movem...

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Abstract

The invention relates to a brain function network feature classification method, which comprises the following steps of: performing format conversion and preprocessing on functional magnetic resonanceimaging, and extracting a time sequence of each brain region; dividing the time sequence into overlapping sub-segments with fixed lengths, and calculating correlation coefficients among the sub-segments to construct a plurality of dynamic function networks; splicing the column vectors of the upper triangular elements of each dynamic brain function network into a function connection vector, and combining all the tested function connection vectors into a successful aggregation matrix; dividing all the tested aggregation matrixes into three parts as samples, wherein each sample is used as a feature subspace; learning and classifying each feature subspace by the training set to obtain a training result; evaluating the network model by the verification set, and adjusting network parameter by the verification set; and classifyings each feature subspace by the test set to obtain a final classification result. The method has a certain reference value for researching cognitive impairment of the brain.

Description

technical field [0001] The invention belongs to the technical field of biomedical information, and relates to a method for classifying features of a brain function network, in particular to a method for classifying features of a brain function network based on a deep polynomial network. Background technique [0002] The human brain is a very complex system that exists in nature. Various types of neurons are connected together through synapses to form a very complex brain structure network, which is the structural basis for various physiological and cognitive activities of the brain. . During the active or passive activity of the brain caused by external stimuli, each neuron or neural dynamic process extends into a complex brain functional network, which is an intuitive description of the changes in brain neural activity. In previous studies, functional connectivity in brain functional networks was a research hotspot. Functional connectivity is closely related to structural ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G06K9/62G06N3/04G06N3/08G16H30/20A61B5/055
CPCG06N3/084G16H30/20A61B5/055G06N3/045G06F18/241
Inventor 焦竹青季一新焦庭轩邹凌曹音张煜东
Owner CHANGZHOU UNIV
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