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Traditional Chinese medicine composition for treating sexual precosity including breast development of children

A composition and precocious technology, applied in the direction of drug combination, disease, medical formula, etc., can solve problems such as unsatisfactory effects, achieve remarkable curative effect, easy to take, and simple production process

Inactive Publication Date: 2019-12-24
浙江中医药大学附属第二医院
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, there are two main types of medicines for treating precocious puberty, one is Chinese patent medicines, but these Chinese patent medicines can only be used for the early stage of precocious puberty. This type of patient may be able to partially delay the growth rate by taking Chinese patent medicines. If the bone age of this patient is more than two years old than his height, the effect of taking Chinese patent medicines is generally not ideal for this patient, and subcutaneous injections of gonadotropin-releasing hormones may be required. Hormone analogues, and even combined application of growth hormone at the same time, can improve her final height. Such patients may need about two years of treatment

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0034] 2019-3-28

[0035] Jiang Moumou, female, 9 years old, has precocious puberty. Breast lump about 5cm*5cm in size, hard texture, pain from time to time, no menstruation, pale fat tongue with thin white and slightly greasy fur, stringy pulse.

[0036] 5 parts of Bupleurum bupleuri, 10 parts of Poria cocos, 10 parts of fried Atractylodes macrocephala, 10 parts of fried white peony root, 6 parts of angelica, 3 parts of roasted licorice, 5 parts of mint, 9 parts of Fritillaria japonicus, and 9 parts of fried blanc , 6 parts of orange core, 10 parts of white tribulus, 12 parts of malt, 15 parts of yam, 12 parts of fried rice sprouts, 5 parts of French pinellia, 10 parts of white mustard seed, 3 parts of patchouli, and take 14 doses of decoction orally.

[0037] 2019-4-11

[0038] The mammary gland mass shrunk significantly to a size of about 4cm*4cm, the texture became soft, no pain, the tongue was pale and fat, the fur was thin, white and slightly greasy, and the pulse was ...

Embodiment 2

[0059] Mao XX, female, 6 years old.

[0060] On September 1, 2018, he was hospitalized for "central precocious puberty and thyroid nodules". He was 125cm tall, weighed 25kg, and his bone age was about two years earlier. The pelvic ultrasound showed that the uterus was anterior, with a size of 14*9*14mm, right The size of the ovary is 12*10*11mm, and there are 6-7 follicles with a diameter of 2-4mm inside. The size of the left ovary is 13*8*12mm, and there are 6-7 follicles with a diameter of 2-5mm inside. Give triptorelin 0.062mg subcutaneous injection, IGF317.2UG / L, sex hormone basal value LH0.1IU / L, FSH1.61IU / L, PRL19.04IU / L, E2: 5ng / L, LHRH excitation: LH peak value: 7.84IU / L, FSH11.61IU / L. MRI of the pituitary gland: the height of the pituitary gland is about 6mm. Thyroid ultrasound: nodular lesions in bilateral lobes. Give GNRH-a injection once. He was discharged from the hospital on September 5.

[0061] 2018-9-5

[0062] The affected side was 6 years old and 8 mon...

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Abstract

The invention relates to a traditional Chinese medicine composition for treating sexual precosity including breast development of children. The traditional Chinese medicine composition is characterized in that effective components of the composition include radix bupleuri, poria cocos, stir-fried bighead atractylodes rhizomes, stir-fried white peony roots, radix glycyrrhizae preparata, mint, thunberg fritillary bulbs, stir-fried cowherb seeds, tangerine seeds, tribulus terrestris, malt and sinapis alba. The composition disclosed by the invention has the function of treating the sexual precosity including breast development of the children. The liver meridian and the stomach meridian pass through breasts, and the radix bupleuri, the mint, the tribulus terrestris, the stir-fried white peonyroots and the malt can soothe the liver and regulate qi; the thunberg fritillary bulbs, the stir-fried cowherb seeds, the tangerine seeds and the sinapis alba can eliminate stagnation and eliminate mass; and infantile spleen and stomach are delicate, the stir-fried bighead atractylodes rhizomes and the licorice roots are administrated to invigorate the spleen and harmonize the stomach, and the effects of soothing the liver, regulating qi, strengthening the spleen, regulating the function of the stomach, eliminating mass and eliminating stagnation can be comprehensively achieved. The effects and beneficial effects on human bodies of the composition prepared from single agents in a certain proportion are much better than those of single agents. The composition is simple in production technology, easy to take and notable in treatment effects, and is an ideal traditional Chinese medicine composition for treating the sexual precosity including breast development of the children.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicines, in particular to a traditional Chinese medicine composition for treating precocious puberty and breast development in children. Background technique [0002] In recent years, with the improvement of people's living standards, there are more and more problems of precocious puberty caused by fast food snacks, poor-quality stationery, bad work and rest, and environmental impact. It is understood that except for a small number of precocious puberty with definite etiology, most of the underlying causes are still unclear. It is a common endocrine disease in children, and the incidence is currently on the rise. [0003] At present, there are two main types of medicines for treating precocious puberty, one is Chinese patent medicines, but these Chinese patent medicines can only be used for the early stage of precocious puberty. This type of patient may be able to partially delay the growth r...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8998A61P5/24A61P15/14
CPCA61K36/076A61K36/185A61K36/233A61K36/284A61K36/31A61K36/36A61K36/484A61K36/534A61K36/65A61K36/71A61K36/752A61K36/8966A61K36/8998A61P5/24A61P15/14A61K2300/00
Inventor 金丽华
Owner 浙江中医药大学附属第二医院
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