Traditional Chinese medicine composition for treating chronic atrophic gastritis

A technology of atrophic gastritis and composition, which is applied in the field of traditional Chinese medicine composition for the treatment of chronic atrophic gastritis, and can solve the problem of lack of specific drugs in western medicine

Inactive Publication Date: 2020-01-10
刘圣梅
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The following types of drugs are mostly used for treatment: gastric mucosa protection drugs, such as sucralfate and smecta; antibiotics, such as clarithromycin, gentamicin; antacids, such as cimetidine, ranitidine; Drugs for gastrointestinal motility function, such as metoclopramide, but the above-mentioned treatments only improve symptoms to a certain extent. Western medicine still lacks specific drugs for the radical cure of CAG and reversal of intestinal metaplasia.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0037] Embodiment 1: the capsule preparation of medicine of the present invention

[0038] Take the following raw materials by weight:

[0039] Periplaneta americana 900g, Radix Astragali 900g, Radix Pseudostellariae 300g, Curcuma 300g, Suluozi 600g, Radix Glycyrrhiza 300g, Fructus Aurantii 300g.

[0040] The above-mentioned crude drug is prepared according to the following method:

[0041] Add water to decoct the crude drug in the weight ratio twice, add 12 times the amount for the first time, decoct for 2 hours, add 10 times the amount for the second time, decoct for 2 hours, combine the medicinal liquid, filter the medicinal liquid, Take the filtrate, concentrate it to a relative density of 1.10-1.15 (60°C), add ethanol to make the alcohol content reach 70%, precipitate, let it stand for 24 hours, absorb the supernatant, recover the ethanol, and obtain the alcohol precipitation liquid; liquid, concentrated, dried, and pulverized to obtain dry paste powder; the obtained dr...

Embodiment 2

[0042] Embodiment 2: the capsule preparation of medicine of the present invention

[0043] Take the following raw materials by weight:

[0044] Periplaneta americana 1200g, Radix Astragali 1200g, Radix Pseudostellariae 400g, Zedoary Curcuma 400g, Su Luozi 800g, Roasted Licorice 400g, Fructus Aurantii 400g.

[0045] The above-mentioned crude drug is prepared according to the following method:

[0046]Add water to decoct the crude drug in the weight ratio twice, add 12 times the amount for the first time, decoct for 2 hours, add 10 times the amount for the second time, decoct for 2 hours, combine the medicinal liquid, filter the medicinal liquid, Take the filtrate, concentrate it to a relative density of 1.10-1.15 (60°C), add ethanol to make the alcohol content reach 70%, precipitate, let it stand for 24 hours, absorb the supernatant, recover the ethanol, and obtain the alcohol precipitation liquid; liquid, concentrated, dried, and pulverized to obtain a dry paste powder; the ...

Embodiment 3

[0047] Embodiment 3: the tablet preparation of medicine of the present invention

[0048] Take the following raw materials by weight:

[0049] Periplaneta americana 600g, Radix Astragali 700g, Radix Pseudostellariae 500g, Curcuma 700g, Suluozi 700g, Radix Glycyrrhizae 600g, Fructus Aurantii 300g.

[0050] The above-mentioned crude drug is prepared according to the following method:

[0051] Add water to decoct the crude drug in the weight ratio twice, add 10 times the amount for the first time, decoct for 1 hour, add 8 times the amount for the second time, decoct for 1 hour, combine the medicinal liquid, filter the medicinal liquid, Take the filtrate, concentrate to a relative density of 1.10-1.15 (60°C), add ethanol to make the alcohol content reach 80%, precipitate, let it stand for 32 hours, absorb the supernatant, concentrate, dry, crush, and use ethanol as a bond The preparation is granulated, dried, and compressed into 1200 tablets.

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PUM

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Abstract

The invention discloses a traditional Chinese medicine composition for treating chronic atrophic gastritis. The composition consists of the following raw materials in parts by weight: 6-12 parts of periplaneta Americana, 4-12 parts of radix astragali, 1-6 parts of radix pseudostellariae, 1-7 parts of rhizoma curcumae, 4-8 parts of semen aesculi, 1-6 parts of rhizoma curcumae, 1-6 parts of glycyrrhizae radix and 1-6 parts of fructus aurantii. The technical scheme of the traditional Chinese medicine composition performs the functions of invigorating spleen, supplementing qi, promoting blood circulation to remove blood stasis, harmonizing stomach, relieving pain and reversing intestinal metaplasia, and can be used for treating gastral cavity pain caused by the spleen and stomach qi deficiencyand blood stasis of the chronic atrophic gastritis, wherein the gastral cavity pain includes gastral cavity fullness and distention as well as pain, mental fatigue and weakness, symptoms, including anorexia, epigastric upset, eructation, sour regurgitation, nausea, bitterness in the mouth and the like, can be accompanied, and symptoms, including tongue lightness and darkness or purple plagues andan uneven and slow pulse or thread and slow pulse, are also accompanied. The traditional Chinese medicine composition can carry out treatment by aiming at disease pathogenesis which causes the chronic atrophic gastritis, alleviates symptoms, is quick in taking effects, addresses both symptoms and root causes and reverses the intestinal metaplasia.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicines, in particular to a traditional Chinese medicine composition for treating chronic atrophic gastritis. Background technique [0002] Chronic atrophic gastritis (CAG for short) is one of the main pathological changes caused by localized or extensive atrophy of the intrinsic glands in the gastric mucosa caused by a variety of etiologies. A chronic gastritis. Since fiber optic and electronic gastroscopy examinations were carried out, the detection rate of CAG accounts for 7.5%-13.8% of the total number of patients examined by gastroscopy, and the annual canceration rate of CAG is 0.5%-1%, and the canceration rate is higher when accompanied by dysplasia. In 1978, the World Health Organization officially listed CAG as the precancerous state of gastric cancer. If it is accompanied by moderate or severe intestinal metaplasia and / or dysplasia, it is a precancerous lesion of gastric cancer (Pre...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9066A61P1/04A61K35/64
CPCA61K35/64A61K36/185A61K36/36A61K36/481A61K36/484A61K36/752A61K36/9066A61P1/04A61K2300/00
Inventor 张爱娟刘圣梅李晓东杨子仪刘学中
Owner 刘圣梅
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