Detection method of transfer volume of ethylenediamine and hexamethylenediamine in food contact materials and products

Abstract

The invention discloses a detection method of the transfer volume of ethylenediamine and hexamethylenediamine in food contact materials and products. The detection method comprises the steps that sampling is performed; and pretreatment and detection of the content of the ethylenediamine and the hexamethylenediamine in a target substance after the pretreatment are performed. The pretreatment step includes the steps that when a sample is a non-oil-based substance, the sample is mixed with a first internal standard solution to form a first mixed solution; the first mixed solution is mixed with afirst extractant, and oscillation treatment is performed at a first preset temperature for the first preset time; and after standing and layering, a supernatant is obtained as a target substance to bedetected. Benzaldehyde is used as a derivatization reagent to convert the ethylenediamine and the hexamethylenediamine into corresponding diaminophenyl compounds, the detection is performed through the independently developed GC-MS, the limit of quantitation of water-based and acidic food and alcohol food simulants can reach 0.5 mg / L, and the limit of quantitation in oil-based food simulants canreach 0.5 mg / kg.

Description

technical field [0001] The invention relates to the detection field, in particular to a detection method for migration of ethylenediamine and hexamethylenediamine in food contact materials and products. Background technique [0002] Ethylenediamine, colorless or yellowish oily or watery liquid, has an ammonia-like smell, is strongly alkaline, CAS No.: 107-15-3, and is mainly used as a solvent, organic synthesis and polymer polymerization. It has strong irritation to mucous membranes and skin, can cause liver and kidney damage, can pollute water bodies, and endanger the environment. In June 2018, ethylenediamine was officially listed by the European Chemicals Agency as the 19th batch of substances of very high concern. [0003] As an important chemical raw material, hexamethylenediamine is mainly used in the production of plastic products such as nylon 66. It is a colorless and transparent crystal at room temperature, with a CAS number of 124-09-4. Toxic substances that have...

AI Technical Summary

Problems solved by technology

Ethyl chloroformate is a colorless liquid, flammable and explosive, and has a pungent odor. Its vapor has a strong irritating effect on the eyes, skin and mucous membranes. Four types of Class B organic highly toxic drugs, relatively high cost of use and storage, and not conducive to human health

GC-FID can basically detect most organic compounds, and has the characteristics of simple structure, rapid response and high sensitivity, but it is easily interfered by other impurities, which is not conducive to qualitative and quantitative

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