Anti-aging eye cream and preparation method therefor

An anti-aging and eye cream technology, applied in the field of anti-aging eye cream and its preparation, can solve the problems of inability to dissolve and disperse, difficult to be absorbed and utilized by the skin, etc., so as to improve the transdermal absorption efficiency and bioavailability, the formula is mild and non-irritating, and the Effects of skin aging

Inactive Publication Date: 2020-02-14
YUNNAN LVXIN BIOLOGICAL PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] Since cannabidiol and astaxanthin are both fat-soluble compounds and insoluble in water, they cannot be di

Method used

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  • Anti-aging eye cream and preparation method therefor
  • Anti-aging eye cream and preparation method therefor

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0030] The preparation method of astaxanthin liposome and cannabidiol liposome is the same, taking cannabidiol as an example, the steps are as follows:

[0031] ①Preparation of the organic phase: Accurately weigh 30 mg of cannabidiol, 300 mg of phospholipids and 100 mg of cholesterol and add them to ethanol, heat and stir to fully dissolve them to obtain an organic phase.

[0032] ② Film production: Evaporate the organic phase obtained in step ① on a rotary evaporator to remove the solvent, so that the residue forms a phospholipid film on the inner wall of the container. The rotary evaporation temperature is 50 ° C and the vacuum degree is 0.1 MPa.

[0033] ③Hydration: Slowly add 20ml of 0.02mol / L phosphate buffer (pH7.0) into the phospholipid film container, and continue rotary steaming for 3 hours to make the phospholipid film fall off to obtain cannabidiol liposome suspension.

[0034] ④ Homogenization: inject the suspension into a high-pressure homogenizer for 3 times for ...

Embodiment 2

[0043] 1. Taking astaxanthin as an example, the preparation method of astaxanthin liposome is described, and the preparation method of cannabidiol liposome is the same, and the specific steps are as follows:

[0044] ①Preparation of the organic phase: Accurately weigh 20 mg of astaxanthin, 300 mg of phospholipid and 100 mg of cholesterol and add them to ethanol, heat and stir to fully dissolve them to obtain an organic phase.

[0045] ② Film production: Evaporate the organic phase obtained in step ① on a rotary evaporator to remove the solvent, so that the residue forms a phospholipid film on the inner wall of the container. The rotary evaporation temperature is 50 ° C and the vacuum degree is 0.1 MPa.

[0046] ③Hydration: Slowly add 20ml of 0.01mol / L phosphate buffer (pH7.5) into the phospholipid film container, and continue rotary steaming for 3h, so that the phospholipid film falls off, and astaxanthin liposome suspension is obtained.

[0047] ④ Homogenization: inject the a...

Embodiment 3

[0056] Taking cannabidiol as an example, the preparation method of cannabidiol liposome is as follows, and the preparation method of astaxanthin liposome is the same.

[0057] ①Preparation of the organic phase: Accurately weigh 10 mg of cannabidiol, 300 mg of phospholipids and 100 mg of cholesterol and add them to ethanol, heat and stir to fully dissolve to obtain an organic phase.

[0058] ② Film production: Evaporate the organic phase obtained in step ① on a rotary evaporator to remove the solvent, so that the residue forms a phospholipid film on the inner wall of the container. The rotary evaporation temperature is 50 ° C and the vacuum degree is 0.1 MPa.

[0059] ③Hydration: Slowly add 20ml of 0.01mol / L phosphate buffer (pH8.0) into the phospholipid film container, and continue rotary steaming for 3 hours to make the phospholipid film fall off to obtain cannabidiol liposome suspension.

[0060] ④ Homogenization: inject the above suspension into a high-pressure homogenizer ...

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Abstract

The invention discloses anti-aging eye cream and a preparation method therefor. Multiple plant active ingredients are added into the eye cream; cannabidiol (CBD) being a hemp extract has a very good anti-oxidation effect, antisepsis and anti-inflammation effects, soothing effect, anti-allergy effect and the like, and astaxanthin is a powerful antioxidant, but is prone to oxidize and unstable. According to the anti-aging eye cream and the preparation method therefor, the liposoluble CBD and the astaxanthin are used to prepare nano-liposomes, and thus, the water solubility and the stability of the CBD and the astaxanthin are improved; meanwhile, transdermal absorption effects of the CBD and the astaxanthin are promoted; the CBD and the astaxanthin rapidly and effectively permeate the skin surface to reach the deep skin and slowly release, and the effects are more lasting. The eye cream has a simple and efficient formula, is safe and mild and easy to absorb, and can effectively scavenge free radicals, moisturize lastingly, slow down ageing of the skin around the eyes and reduce fine wrinkles of the eyes.

Description

technical field [0001] The invention belongs to the technical field of cosmetics, and in particular relates to an anti-aging eye cream and a preparation method thereof. Background technique [0002] There are no sebaceous glands in the eyes, so the skin around the eyes is relatively dry and dehydrated, resulting in fine lines and dry lines. It is the most prone to aging, so eye cream is very necessary. But many people fall into a misunderstanding: the more active ingredients in skin care products, the better: if the skin does not absorb them, it will be a burden. Excess nutrition on the skin surface will cause "skin oxidation" and accelerate skin aging. The problem of absorption is currently a problem that many eye creams are difficult to break through. Therefore, developing an anti-aging eye cream that is easily absorbed by the skin has a broad market prospect. [0003] Cannabidiol (CBD), the main active ingredient in industrial hemp extract, is a powerful antioxidant that...

Claims

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Application Information

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IPC IPC(8): A61K8/9794A61K8/14A61K8/31A61K8/34A61K8/35A61K8/67A61K8/68A61K8/73A61K8/92A61K8/9789A61Q19/00A61Q19/08
CPCA61K8/14A61K8/31A61K8/345A61K8/347A61K8/35A61K8/673A61K8/68A61K8/735A61K8/922A61K8/9789A61K8/9794A61K2800/413A61K2800/56A61K2800/592A61Q19/005A61Q19/08
Inventor 刘胜贵王钲霖薛红芬付彬彬李智高孔令羽
Owner YUNNAN LVXIN BIOLOGICAL PHARMA CO LTD
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