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Methods for real-time image guided radiation therapy

A technology of radiotherapy and imaging, applied in radiotherapy, instruments for radiological diagnosis, treatment, etc., can solve the problem of inability to update or correct radiation in real time

Active Publication Date: 2020-04-10
REFLEXION MEDICAL INC
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Failure to update or correct delivery of radiation in real time to account for patient and / or tumor motion that may result in delivery of radiation to non-target regions

Method used

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  • Methods for real-time image guided radiation therapy
  • Methods for real-time image guided radiation therapy
  • Methods for real-time image guided radiation therapy

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Embodiment Construction

[0036] Disclosed herein are systems and methods for guiding the delivery of therapeutic radiation using incomplete or partial images and / or image data acquired during a treatment session. Some methods may include acquiring a partial image of a target region of the patient and multiplying it with a radiation excitation matrix. The radiation excitation matrix can be calculated during the treatment planning session based on the same data set used to calculate the treatment plan. The treatment plan may be pre-generated using patient images acquired during diagnostic imaging and / or previous treatment sessions. The treatment plan may contain a map or matrix identifying one or more patient target regions (e.g., radiation target regions such as planning target volumes or PTVs) and each target region to be delivered to the one or more target regions expected radiation dose. A Radiation Firing Matrix (RFM) may be a matrix specifying the transformation from a partial image to a fluence...

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Abstract

Disclosed herein are systems and methods for guiding the delivery of therapeutic radiation using incomplete or partial images acquired during a treatment session. A partial image does not have enoughinformation to determine the location of a target region due to, for example, poor or low contrast and / or low SNR. The radiation fluence calculation methods described herein do not require knowledge or calculation of the target location, and yet may help to provide real-time image guided radiation therapy using arbitrarily low SNR images.

Description

[0001] Cross References to Related Applications [0002] This application claims priority to U.S. Provisional Patent Application No. 62 / 512,632, filed May 30, 2017, and U.S. Provisional Patent Application No. 62 / 37,384, filed July 26, 2017, the entire disclosures of which are incorporated by reference at this. technical field [0003] Disclosed herein are systems and methods for guiding the delivery of therapeutic radiation using incomplete or partial images and / or image data acquired during a treatment session. Background technique [0004] Image guided radiation therapy (IGRT) uses images acquired prior to a treatment session to guide the application of therapeutic radiation during a treatment session. The goal of an IGRT system is to deliver precise doses of radiation to fixed or moving targets within the patient and avoid irradiating risky organs. This typically includes generating a treatment plan that accounts for target motion prior to a treatment session as well as...

Claims

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Application Information

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IPC IPC(8): A61N5/10A61B6/03A61B6/54
CPCA61N5/103A61N5/1039A61N5/1049A61N5/1071A61N5/1075A61B6/032A61B6/037A61B6/00A61B5/055A61N2005/1055A61N2005/1052A61N2005/1061A61N2005/1074A61N5/1067A61N5/1031A61N5/1036A61N5/1045A61N5/1065A61N5/1081A61N2005/1091A61N5/1068
Inventor Y·沃罗年科P·D·奥尔科特D·帕尔R·巴萨洛
Owner REFLEXION MEDICAL INC
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