A preparation process of a liquid medicine filter membrane and a medicine liquid filter membrane

A preparation process and filter technology, applied in the field of particle, bacteria and virus filtration, can solve the problems of easy adsorption of active ingredients of drugs, low material strength, long filtration path, etc., to meet the requirements of ultrafiltration filtration, high structural strength, Filter the effect of short paths

Active Publication Date: 2022-04-12
常州费曼生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Organic materials have good mass production performance, but they also face the problems of material swelling, long filtration path, easy adsorption of active ingredients of drugs, and low material strength, etc.

Method used

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  • A preparation process of a liquid medicine filter membrane and a medicine liquid filter membrane

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preparation example Construction

[0027] The invention provides a preparation process of a liquid medicine filter membrane and a medicine liquid filter membrane. Those skilled in the art can learn from the content of this article and appropriately improve the process parameters to realize it. In particular, it should be pointed out that all similar substitutions and modifications are obvious to those skilled in the art, and they all belong to the protection scope of the present invention. The process and application of the present invention have been described through preferred embodiments, and relevant personnel can obviously make changes or appropriate changes and combinations to the process and application herein without departing from the content, spirit and scope of the present invention to realize and apply the present invention Invent technology.

[0028] like figure 1 Shown, a kind of preparation technology of liquid medicine filter membrane, contains in the step of technology:

[0029] Select an ori...

Embodiment 1

[0044] like figure 1 As shown, taking the dual-channel AAO filter membrane as an example, one-sided etching was performed with a sodium hydroxide solution with a weight percentage of 5-10wt%, and the thickness of the filter membrane was finally reduced to 2 microns. Specifically include the following steps:

[0045] (1) The original filter membrane 2 (AAO) of porous anodic aluminum oxide with a pore size of 100 nanometers is selected, and the film thickness is more than 50 microns. The diameter is 25 mm.

[0046] (2) Prepare the etching solution 3, that is, a sodium hydroxide solution with a weight percentage of 5-10 wt.%. The etching solution 3 is placed in a cylindrical container with an open top, and the hole diameter is 20 mm. The bottom of the container is connected with an inlet pipeline for injecting fresh etching solution.

[0047] (3) Hold the original filter membrane 2 to be thinned with plastic tweezers and place it at the top opening of the container. Simultane...

Embodiment 2

[0050] like figure 1 As shown, taking the dual-channel AAO filter membrane as an example, the phosphoric acid solution with a weight percentage of 5wt% was used for single-sided etching, and finally the thickness of the filter membrane was reduced to 500 nm. Include the following steps:

[0051] (1) The original filter membrane 2 (AAO) of porous anodic aluminum oxide with a pore diameter of 50 nanometers is selected, the film thickness is more than 50 microns, the filter hole 1 is a double channel, that is, it is connected to both sides of the front and back, and the original filter membrane 2 is overall external The diameter is 25 mm.

[0052] (2) Prepare etching solution 3, that is, phosphoric acid solution with a weight percentage of 5wt%, and place etching solution 3 in a container with an open top, and its pore diameter is 20 mm. The bottom of the container is connected with an inlet pipeline for injecting fresh etching solution.

[0053] (3) Hold the original filter m...

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Abstract

The invention discloses a preparation process of a liquid medicine filter membrane and a medicine liquid filter membrane. The steps of the process include: selecting an original filter membrane with through filter holes; Etching solution is used for etching, and positive pressure gas is blown from the top side of the original filter membrane to obtain a thinned liquid medicine filter membrane; wherein, the blowing direction of the positive pressure gas is from top to bottom, In order to prevent the etching solution from flowing from the filter holes to the inside of the filter membrane, the etching solution is restricted to only etch from the bottom surface of the original filter membrane. The invention realizes the processing of ultra-thin filter membrane with nanometer filter holes, and effectively reduces flow resistance and pressure difference.

Description

technical field [0001] The invention relates to a preparation process of a liquid medicine filter membrane and a medicine liquid filter membrane, belonging to the field of particle, bacteria and virus filtration in medical equipment and medicine production. Background technique [0002] At present, during the production, transportation and use of medicinal liquids, the safety of medicinal liquids needs to be strictly controlled. In the process of use, the drug solution entering the vein through the infusion set needs to strictly control the particle pollution and possible bacterial contamination in the drug solution. For example, for infants and young children, due to the immature blood vessel development, the diameter of the blood vessel is small, so in the process of infusion therapy, once particle pollution and blockage occur, it is very likely to seriously endanger life safety. The national standard GB8368 (2005) clearly stipulates the particle diameter requirements for...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): B01D71/02B01D67/00
CPCB01D71/025B01D67/0039
Inventor 蒋开朱学林
Owner 常州费曼生物科技有限公司
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