Unlock instant, AI-driven research and patent intelligence for your innovation.

Iron-based metal-organic framework material loaded with silver nanoparticles and its preparation method and application

A technology of silver nanoparticles and iron-based metals, applied in the field of materials, can solve the problem of short-term antibacterial effect

Active Publication Date: 2022-03-01
QUZHOU UNIV +3
View PDF0 Cites 1 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The purpose of the present invention is to overcome the short-lived antibacterial effect caused by the explosive release of silver nanoparticles in the prior art, and provide an iron-based metal-organic framework material loaded with silver nanoparticles and its preparation method and application

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0021] The first aspect of the present invention provides a method for preparing an iron-based metal-organic framework material loaded with silver nanoparticles, the method comprising the following steps:

[0022] (1) Dissolve the iron salt and the organic ligand in an organic solvent in a molar ratio of 1:(1-4), then react at 100-160°C for 3-6 days, then wash and dry in sequence to obtain the first a product;

[0023] (2) Add the first product obtained in step (1) to an organic solvent containing silver ions, and control the mass ratio of the first product to silver ions to be 1: (2-6), and then set the temperature at 60-80° C. Down reaction 3-4 days, obtain the second product;

[0024] (3) Disperse the second product obtained in step (2) and ascorbic acid in an organic solvent according to the molar ratio of 1: (1-4), and add lye to adjust the pH value to 8-11, and then at 70-110°C After 3-6 days of reaction, an iron-based metal-organic framework material loaded with silve...

Embodiment 1

[0051] (1) Anhydrous ferric chloride and terephthalic acid were dissolved in N,N-dimethylformamide at a molar ratio of 1:2, then reacted at 110°C for 3 days, and then washed three times with ethanol, Then dry to obtain the first product;

[0052] (2) the first product that step (1) gained is joined in the N, N-dimethylformamide that contains silver ion, and the mass ratio that controls described first product and silver ion is 1:4, then at 60 Reaction at ℃ for 3 days to obtain the second product;

[0053] (3) The second product obtained in step (2) and ascorbic acid are dispersed in N,N-dimethylformamide according to the molar ratio of 1:1, and the NaOH solution of 0.5mol / L is added to adjust the pH value to 10, and then React at 90° C. for 3 days to obtain iron-based metal-organic framework material A1 loaded with silver nanoparticles.

[0054] The iron-based metal-organic framework material A1 loaded with silver nanoparticles can completely inhibit bacterial proliferation ...

Embodiment 2

[0056] (1) Fe(NO 3 ) 3 9H 2 O and 2-aminoterephthalic acid were dissolved in N,N-dimethylacetamide at a molar ratio of 1:1, then reacted at 100°C for 4 days, followed by three washes with ethanol, and then dried to obtain first product;

[0057] (2) the first product that step (1) gained is joined in the N, N-dimethylacetamide that contains silver ion, and the mass ratio that controls described first product and silver ion is 1:3, then at 70 Reaction at ℃ for 3 days to obtain the second product;

[0058] (3) The second product obtained in step (2) and ascorbic acid are dispersed in N,N-dimethylacetamide according to the molar ratio of 1:2, and the NaOH solution of 0.4mol / L is added to adjust the pH value to 9, and then React at 100° C. for 3 days to obtain iron-based metal-organic framework material A2 loaded with silver nanoparticles.

[0059] The iron-based metal-organic framework material A2 loaded with silver nanoparticles can completely inhibit bacterial proliferatio...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention relates to the field of materials, in particular to an iron-based metal-organic framework material loaded with silver nanoparticles and a preparation method and application thereof. The method comprises: (1) reacting the iron salt and the organic ligand at a molar ratio of 1:(1-4) at 100-160°C for 3-6 days, followed by washing and drying in sequence to obtain the first product; (2) Control the mass ratio of the first product and the silver ion to be 1: (2-6), react at 60-80° C. for 3-4 days to obtain the second product; (3) mix the second product and ascorbic acid according to molar The ratio is 1:(1‑4) dispersed in an organic solvent, and the pH value is adjusted to 8‑11, and then reacted at 70‑110 °C for 3‑6 days. The material can realize the loading and slow release of silver nanoparticles, so that the prepared iron-based metal-organic framework material loaded with silver nanoparticles has sustained slow release and continuous and durable antibacterial effects.

Description

technical field [0001] The invention relates to the field of materials, in particular to an iron-based metal-organic framework material loaded with silver nanoparticles and a preparation method and application thereof. Background technique [0002] Antibiotics can greatly reduce the death caused by microbial pathogen infection. In recent years, due to the abuse of antibiotics, many drug-resistant superbugs have become a new threat to human health. Scientists have found that metallic silver nanoparticles (AgNP) have good application prospects in curbing bacterial and microbial infections. However, silver nanoparticles will explode during use, resulting in only a short-term antibacterial effect. [0003] Metal-organic frameworks (MOFs) are a new kind of porous crystalline materials in recent decades, which are self-assembled through coordination with metal ions or metal clusters as nodes and organic ligands as linking units. Crystalline materials in one, two or three dimensi...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Patents(China)
IPC IPC(8): A61K47/12A01N59/16A01N25/10A01P3/00A01P1/00A61K33/38A61K9/52A61K47/22A61P31/04A61P29/00
CPCA01N59/16A01N25/10A61K33/38A61K9/5123A61P31/04A61P29/00
Inventor 贺庆余世桨林文鑫黄霞娟覃克奎曹波二韩沅伯赵虹官兴华
Owner QUZHOU UNIV
Features
  • R&D
  • Intellectual Property
  • Life Sciences
  • Materials
  • Tech Scout
Why Patsnap Eureka
  • Unparalleled Data Quality
  • Higher Quality Content
  • 60% Fewer Hallucinations
Social media
Patsnap Eureka Blog
Learn More

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2025 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com