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A Water Maze Apparatus in the Experimental Study of Cognitive Impairment in Rats with Cerebral Ischemia

A technology for cognitive dysfunction and experimental research, applied in the field of maze devices, can solve the problems of high overall height of the platform, optical refraction at the bottom of the platform, visual confusion of rats, etc.

Inactive Publication Date: 2021-09-10
PEOPLES HOSPITAL OF HENAN PROV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0012] The purpose of the present invention is to provide a maze device in the experimental research of cerebral ischemic rat cognitive dysfunction, to solve the problem that the overall height of the platform in the prior art is high, and the bottom of the platform is easy to produce optical refraction and cause damage to the rat's vision. confusing technical issues

Method used

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  • A Water Maze Apparatus in the Experimental Study of Cognitive Impairment in Rats with Cerebral Ischemia
  • A Water Maze Apparatus in the Experimental Study of Cognitive Impairment in Rats with Cerebral Ischemia
  • A Water Maze Apparatus in the Experimental Study of Cognitive Impairment in Rats with Cerebral Ischemia

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Embodiment Construction

[0025] Examples of the water maze device in the experimental study of cerebral ischemic rat cognitive dysfunction Figure 1~5 Shown: includes a pool 1 and a platform 2 for floating in the pool, the pool 1 includes a pool wall 6 and a pool bottom 5, the platform 2 includes a buoyancy box with a buoyancy chamber 7, and a magnetic body 9 is arranged on the platform. The water maze device also includes a magnet 4 for being fixed on the bottom of the pool to absorb the magnetic body. The magnet 4 in the present invention is a permanent magnet, and the volume of the buoyancy chamber 7 is adjustable.

[0026]The buoyancy box comprises a buoyancy box bottom wall 11, a buoyancy box cover body 13 fixed on the buoyancy box front side wall 18 between the buoyancy box bottom wall and the buoyancy box cover body, the buoyancy box rear side wall 19 and the buoyancy box right side wall 12, the buoyancy The top of the box cover body 13 forms the platform platform, and the buoyancy box also inc...

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Abstract

The present invention relates to a kind of water maze device in the experimental research of the cerebral ischemic rat cognitive dysfunction, comprises the water pool that constitutes by pool wall and pool bottom, also comprises the platform that is used for floating in described water pool, and platform comprises A buoyancy box with a buoyancy chamber, a magnetic body is arranged on the platform, and the water maze device also includes a magnet for being fixed on the underside of the pool bottom to absorb the magnetic body, and the volume of the buoyancy chamber is adjustable and / or The magnetic force of the magnet is adjustable. The present invention provides a labyrinth device in the experimental research of cognitive dysfunction in cerebral ischemic rats, to solve the problems in the prior art that the overall height of the platform is high, and the bottom of the platform is easy to produce optical refraction, which confuses the vision of rats technical problem.

Description

technical field [0001] The invention relates to a labyrinth device in the experimental research of cerebral ischemic rat cognitive dysfunction in the field of animal experiments. Background technique [0002] Chronic cerebral circulation insufficiency (CCCI) was proposed by Japanese scholars in 1990, which refers to the fluctuation of subjective symptoms such as headache and dizziness caused by cerebral arterial circulation disturbance. At present, there is no exact and generally accepted definition of CCCI, but it is generally considered to be a common ischemic cerebrovascular disease, which exists in about 2 / 3 of people over 60 years old. CCCI is closely related to many cerebrovascular diseases, especially vascular dementia (VD) and Alzheimer's disease (AD). degree. Cerebral circulation disorders caused by various reasons can cause insufficient blood supply to the brain. Long-term CCCI causes chronic ischemia in the brain, resulting in varying degrees of pathological dam...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A01K15/02
CPCA01K15/027
Inventor 张广林李天晓常晓赞行君
Owner PEOPLES HOSPITAL OF HENAN PROV