Ligustrum lucidum ait fruit extract, granules containing ligustrum lucidum ait fruit extract and preparation process of granules

A preparation process and a technology of Ligustrum lucidum, applied in the field of Ligustrum lucidum extract, can solve problems such as unfavorable taking, and achieve the effects of enhanced preparation quality and simple and convenient preparation process method.

Inactive Publication Date: 2020-11-03
ANHUI SCI & TECH UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Ligustrum lucidum has a hard texture and is unfavorable for taking. There is no relevant granule and preparation method thereof on the market, and it is urgent to further improve the machine.

Method used

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  • Ligustrum lucidum ait fruit extract, granules containing ligustrum lucidum ait fruit extract and preparation process of granules
  • Ligustrum lucidum ait fruit extract, granules containing ligustrum lucidum ait fruit extract and preparation process of granules
  • Ligustrum lucidum ait fruit extract, granules containing ligustrum lucidum ait fruit extract and preparation process of granules

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] Embodiment 1, the preparation of Ligustrum lucidum extract

[0025] 1. Pretreatment of Ligustrum lucidum samples

[0026] Wash the ripe fruit of Ligustrum lucidum twice with water, put it into an electric heating constant temperature drying box for several hours to dry, then crush it into powder with a universal high-speed pulverizer, pass through a 40-mesh sieve to obtain dry Ligustrum lucidum powder, and set aside.

[0027] 2. Preparation of raw materials

[0028] After the above treatment, take 50g powder of privet fruit medicinal material, add 500ml of distilled water to decoct for 2.5h and extract the filtrate, then add 400ml of distilled water to decoct for 1.5h in the filter residue, extract the filtrate after filtering, finally, combine the extracted filtrate and concentrate to Appropriate amount, the concentrated solution is taken out and placed in an evaporating dish for evaporation to obtain the Ligustrum lucidum extract, which is the Ligustrum lucidum extra...

Embodiment 2

[0029] Embodiment 2, preparation of the granule process optimization of Ligustrum lucidum extract: determination of extractum and adjuvant (lactose powder: dextrin)

[0030] It is planned to add 70% ethanol concentration, and the ratio of extract and auxiliary material (lactose powder: dextrin) is 1:1:1, 1:2:1, 1:3:1, 1:1: 2. 1:1:3, as can be seen from Table 1, the granulation process and granule properties are better according to the ratio of prescription 1, 2, 3, so we choose prescription 1:1:1, 1:2:1, 1 :3:1 was used as three levels of orthogonal experiments to carry out follow-up experiments. The experimental results are shown in Table 1, and the properties of each group of prescription granulation were analyzed.

[0031] Table 1 Analysis of properties of prescription granulation in each group

[0032]

Embodiment 3

[0033] Example 3, Process optimization for preparing granules of Ligustrum lucidum extract-determination of drying temperature

[0034] The ratio of extract and auxiliary material (lactose powder: dextrin) to be added is 1:2:1, and the drying temperature is 50°C, 60°C, 70°C, 80°C, 90°C with 70% ethanol concentration, which can be obtained from Table 2 It can be seen that the analysis of the properties of each group of drying temperature granulation, according to the investigation of the properties of the granules obtained at the drying temperatures of prescriptions 2, 3 and 4, the appearance of the granules prepared at the drying temperatures of 60°C, 70°C, and 80°C has uniform size and moisture content. The content effect is better, and the follow-up experiments are carried out as three levels of orthogonal experiments.

[0035] The character analysis of each group drying temperature granulation in table 2

[0036]

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Abstract

The invention discloses a ligustrum lucidum ait fruit extract, granules containing the ligustrum lucidum ait fruit extract and a preparation process of the granules. Wherein the ligustrum lucidum aitfruit extract is prepared by crushing ligustrum lucidum ait fruits into ligustrum lucidum ait fruit powder, adding water to decoct the ligustrum lucidum ait fruit powder, performing filtering, takingfiltrate to obtain filtrate to be concentrated, and concentrating the filtrate to be concentrated to obtain the ligustrum lucidum ait fruit extract. The preparation process of the granules containingthe ligustrum lucidum ait fruit extract comprises the following steps of taking the ligustrum lucidum ait fruit extract, lactose powder and dextrin in proportion, performing uniform mixing to obtain amixture, adding an ethanol wetting agent into the mixture, and performing drying to obtain the granules. Main components in the ligustrum lucidum ait fruit aqueous extract are extracted to prepare the granules, so that the granules are convenient to take, nutrient components of the ligustrum lucidum ait fruits can be more efficiently utilized and absorbed, and human immunity can be improved.

Description

technical field [0001] The invention relates to the technical field of medicine preparation, in particular to a Ligustrum lucidum extract, a granule containing the extract and a preparation process thereof. Background technique [0002] Ligustrum lucidum is the ripe fruit of Ligustrum lucidum Ait, which belongs to the genus Ligustrum lucidum Ait. It has the benefits of strengthening the body and nourishing the body, healthy hair and eyes, and is used for liver and kidney deficiency, dizziness, tinnitus, and body Weakness, premature graying of hair and other disease symptoms. Many components in the water extract of Ligustrum lucidum, such as polysaccharides, have the benefits of enhancing the body's own immunity, preventing excessive oxidation, and delaying aging. Domestically, there have been many reports on the polysaccharide research of Ligustrum lucidum. The polysaccharide component in Ligustrum lucidum water extract is one of the plant substances of Ligustrum lucidum w...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/638A61K9/16A61K47/36A61K47/26A61P37/04A61P39/06A61K131/00
CPCA61K9/1623A61K9/1652A61K36/638A61K2236/331A61K2236/39A61K2236/51A61P37/04A61P39/06
Inventor 高亮亮
Owner ANHUI SCI & TECH UNIV
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