Rapid combined detection device for novel coronavirus antigen and antibody in saliva and preparation method thereof

Abstract

A rapid combined detection device for novel coronavirus antigens and antibodies in saliva comprises a clamping shell, a collecting bottle containing treating fluid and a sampling swab, and an antigendetection test strip and an antibody detection test strip are arranged on the clamping shell side by side; each of the antigen detection test strip and the antibody detection test strip comprises a back plate as well as a sample pad, a gold-labeled pad, an NC membrane and water absorption filter paper which are sequentially connected and arranged on the back plate, a detection line and a quality control line are arranged on the upper surface of the NC membrane, the quality control line is arranged on one side close to the water absorption paper, and the detection line is arranged on one side close to the sample pad; the rapid joint detection device for the novel coronavirus antigen and antibody in saliva is simple and convenient in sampling, easy to accept by testees, capable of effectively reducing infection risks of medical staff, safer and noninvasive in sampling, free of large equipment and instruments, simple in operation, easy in result judgment, suitable for self-detection of large-scale crowds and high in sensitivity. The antigen and antibody combined detection can shorten the window period and has high sensitivity.

Description

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AI Technical Summary

Benefits of technology

This new technology allows researchers to quickly detect small amounts (<100 mL) of virus that may cause respiratory illnesses like COVID-19. By combining this data from multiple samples together it becomes easier to determine which ones have caused these diseases better than other methods such as testing them on their own. Additionally, there's an advantage over current tests where patients must wait until they become sick before getting tested because many viruses only infect humans but some others still spread through contaminated surfaces. Overall, this innovation provides technical benefits that make it possible to improve healthcare outcomes while reducing risks associated with traditional diagnoses techniques.

Problems solved by technology

This patented technical problem addressed by this patents relates to developing a quick assay system for identifying unknown strains associated with New Coronovims disease caused by bacteria called SARS CoV-2. Current methods require multiple steps involving extraction from patient fluids followed up on specialized tests like ELISA, Western Blotting, polymerase chain reaction analysis, flow cell culture, and others requiring trained individuals.

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