Whole-brain individualized brain function map construction method based on independent component network

A technology of independent components and construction methods, applied in the field of whole-brain individualized brain function map construction, can solve the problems of not fully considering the distribution differences of brain function sub-regions, lack of functional correspondence, etc.
CN112002428BActive Publication Date: 2022-03-08TIANJIN MEDICAL UNIV
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
TIANJIN MEDICAL UNIV
Publication Date
2022-03-08

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Abstract

The invention is a method for constructing a whole-brain individualized brain function atlas with reference to an independent component network. The method utilizes the resting-state fMRI data of individual subjects, firstly introduces an independent component analysis method to construct a group-level brain function sub-network, and then Using spatiotemporal regression to inversely reconstruct the brain functional sub-network of each subject and the characteristic time series corresponding to the functional sub-network, and use the characteristic time series corresponding to the functional sub-network as a reference signal; introduce inverse distance weighting coefficients, sub-network inverse variation Coefficient weighting, correlation factor, and iterative process are used to obtain a whole-brain individualized functional map with the independent component network as the reference. This method has the advantages of being purely data-driven, completely corresponding to brain regions, covering the whole brain, and more flexible in functional brain region segmentation. tool.
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Description

Technical field:

[0001] The present invention relates to the technical field of brain function atlas construction, in particular to a whole-brain individual with independent component network as a reference given by using brain resting-state functional magnetic resonance imaging (rs-fMRI) data. A method for constructing a functional map of the brain. Background technique:

[0002] The human brain is one of the most mysterious and complex nervous systems, containing approximately hundreds of millions of neurons in itself. Moreover, these neurons are interconnected to form a huge neural network. However, current research scholars' understanding of it is still limited. Therefore, if you want to understand this complex network, the most important thing is to understand the nodes that make up the network, which requires building a human brain map that is more refined, more accurate, and more suitable for brain science research.

[0003] Functional magnetic resonance imaging (f...

Claims

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