Traditional Chinese medicine composition for inhibiting helicobacter pylori and application thereof

A technology of Helicobacter pylori and a composition, applied in the field of medical and health care, can solve the problems of increasing the drug resistance of Helicobacter pylori, increasing the difficulty of treatment, and recurring disease, so as to improve bioavailability, kill Helicobacter pylori, and inhibit infection. Effect

Inactive Publication Date: 2021-02-02
滁州向日葵药业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The prior art uses a large dose of multiple antibiotics to kill Helicobacter pylori at the same time. Although antibiotics can solve oral problems, they will cause certain side effects on the human body at the same time, and increase the drug resistance of Helicobacter pylori, which will easily lead to recurrent disease. Increased difficulty of treatment

Method used

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  • Traditional Chinese medicine composition for inhibiting helicobacter pylori and application thereof
  • Traditional Chinese medicine composition for inhibiting helicobacter pylori and application thereof
  • Traditional Chinese medicine composition for inhibiting helicobacter pylori and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0033] A toothpaste for inhibiting Helicobacter pylori, by weight percentage, comprising: 0.2% active ingredient; the balance is toothpaste base;

[0034] Wherein, the active ingredients include: 3 parts of glycyrrhetinic acid, 0.1 part of thymol, 1 part of paeonol, 0.5 part of peppermint oil, 3.5 parts of eucalyptus oil and 0.1 part of lactoferrin in parts by weight;

[0035] Toothpaste base, by weight percentage, includes: glycerin 15%; hydroxymethylcellulose 3%; sodium lauryl sulfate 1%; calcium carbonate 20%; sorbitol 2%; silicon dioxide 2%; 0.5%; the balance of deionized water;

[0036] The raw materials of each component are fully stirred and mixed, and then put into a toothpaste making machine for homogeneous emulsification for 45 to 75 minutes to obtain the toothpaste.

Embodiment 2

[0038] A toothpaste for inhibiting Helicobacter pylori, by weight percentage, comprising: 2% active ingredient; the balance is toothpaste base;

[0039] Wherein, the active ingredients include, by weight parts, 5 parts of glycyrrhetinic acid, 1 part of thymol, 2 parts of paeonol, 1 part of peppermint oil, 2 parts of eucalyptus oil and 1 part of lactoferrin;

[0040] Toothpaste base, by weight percentage, includes: glycerin 20%; hydroxymethylcellulose 2%; sodium lauryl sulfate 3%; calcium carbonate 10%; sorbitol 6%; silicon dioxide 1%; essence 1%; the balance of deionized water;

[0041] The raw materials of each component are fully stirred and mixed, and then put into a toothpaste making machine for homogeneous emulsification for 45 to 75 minutes to obtain the toothpaste.

Embodiment 3

[0043] A toothpaste for inhibiting Helicobacter pylori, comprising: 5% of active ingredients; the remainder is toothpaste base;

[0044] Wherein, the active ingredients are calculated in parts by weight, including: 1 part of glycyrrhetinic acid, 0.5 part of thymol, 0.2 part of paeonol, 0.1 part of peppermint oil, 0.5 part of eucalyptus oil and 0.5 part of lactoferrin;

[0045] Toothpaste base, by weight percentage, includes: 35 parts of glycerin; 1 part of hydroxymethylcellulose; 2 parts of sodium lauryl sulfate; 30 parts of calcium carbonate; 0.5 parts of sorbitol; 3 parts of silicon dioxide; essence 1 part; the balance of deionized water;

[0046] The raw materials of each component are fully stirred and mixed, and then put into a toothpaste making machine for homogeneous emulsification for 45 to 75 minutes to obtain the toothpaste.

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Abstract

The invention discloses a traditional Chinese medicine composition for inhibiting helicobacter pylori. The composition comprises the following components in parts by weight of 1-5 parts of glycyrrhetinic acid and 0.1-1.5 parts of thymol. The invention further discloses application of the traditional Chinese medicine composition in oral hygiene products. According to the invention, the glycyrrhetinic acid and the thymol are used as main active components; the synergistic effect is achieved through compounding of the glycyrrhetinic acid and the thymol; and the composition has the effects of significantly inhibiting the helicobacter pylori and relieving halitosis, does not contain an anti-bactericide component, reduces the generation of drug-resistant bacteria, and has better use safety.

Description

technical field [0001] The invention relates to the technical field of medical treatment and hygiene, and more specifically relates to a traditional Chinese medicine composition for inhibiting Helicobacter pylori and its application. Background technique [0002] Helicobacter pylori is a microaerophilic helicobacter that colonizes in the oral cavity, gastric mucosa and other areas. The main pathogenic factor of gastric mucosa-associated lymphoid tissue (MALT) lymphoma and gastric cancer; the World Health Organization declared gastric Helicobacter pylori as a microbial carcinogen, and it was the first prokaryotic organism confirmed to be carcinogenic to humans. [0003] As the entrance to the digestive tract, the presence of H. pylori in the oral cavity affects the efficacy of H. pylori eradication therapy. Paying attention to oral hygiene and preventing diseases from entering the mouth have become more and more important measures to prevent Helicobacter pylori infection, ha...

Claims

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Application Information

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IPC IPC(8): A61K31/56A61K8/9789A61K8/63A61K8/35A61K8/34A61K8/64A61P31/04A61P1/02A61P29/00A61Q11/00A61K38/40A61K31/05A61K31/12
CPCA61K8/347A61K8/35A61K8/63A61K8/64A61K31/05A61K31/12A61K31/56A61K36/534A61K36/61A61K38/40A61K2800/592A61K2800/805A61Q11/00A61K8/9789A61P1/02A61P29/00A61P31/04A61K2300/00
Inventor 秦德涛陈英
Owner 滁州向日葵药业有限公司
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