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Systems, devices and methods for the treatment of oral and pharyngeal disorders

A pharynx and delivery device technology, applied in the field of systems intervening oral and pharyngeal diseases, can solve the problems of poor patient tolerance and compliance, uncommon curative effects, and inability to provide muscle stimulation.

Pending Publication Date: 2021-03-09
琳妮比尔斯顿 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

These systems are fully implantable and cannot provide noninvasive or minimally invasive muscle stimulation
Also, they don't work for everyone
[0010] For other treatments, such as the delivery of continuous positive airway pressure or mandibular advancement splints, there have been reports of poor patient tolerance and compliance or ineffective efficacy

Method used

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  • Systems, devices and methods for the treatment of oral and pharyngeal disorders
  • Systems, devices and methods for the treatment of oral and pharyngeal disorders
  • Systems, devices and methods for the treatment of oral and pharyngeal disorders

Examples

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Embodiment Construction

[0053] Although the invention has been described with reference to certain embodiments described in detail herein, other embodiments can achieve the same or similar results. Variations and modifications of the present invention will be apparent to those skilled in the art, and the present invention is intended to cover all such modifications and equivalents.

[0054] Preferred embodiments of the present invention will now be described, by way of example only, with reference to the accompanying drawings.

[0055] best as figure 1 As shown, ion channels 1 formed in muscle cells or nerve cells are closed 2 when the cells are in an inactive state. Application of a stimulus in the form of light, a magnetic field, or a chemical3 causes ion channels to open4. This causes ions to flow into the 5 cell or out of the 6 cell, which activates the cell. When the ion channel is formed in muscle cells 7, activation of muscle cells results in Ca 2+ into the muscles. This triggers the rela...

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PUM

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Abstract

Herein are provided systems, devices, and methods for the treatment of oral and pharyngeal disorders via the stimulation of pharyngeal muscles. Contraction of the pharyngeal muscle cells (9) is induced by activation of at least one ion channel (1) formed in at least one of a muscle cell and a neural cell. The ion channel opens (4) when it is activated by a stimulus (3). This allows ions to flow into (5) and out of (6) the cell, causing muscle contraction. This muscle contraction can be targeted towards specific muscles depending upon the condition to be treated.

Description

technical field [0001] The present invention relates to systems, devices and processes for intervention in diseases of the oral cavity and pharynx. However, it will be understood that the invention is not limited to this particular field of use. Background technique [0002] Any discussion of prior art throughout the specification should in no way be considered as an admission that such prior art is well known or forms part of the common general knowledge in the art. [0003] Activation of excitable cells, such as nerve cells and muscle cells, is achieved by introducing into the excitable cells receptors or ion channels that respond to stimuli that are not normally present in normal animals, including humans. These receptors and ion channels can be designed or selected to respond to non-physiological stimuli such as light (optogenetics), chemicals (chemogenetics) or magnetic fields (magnegenetics). [0004] Optogenetics is the use of light to stimulate excitable cells by g...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61N5/06A61K48/00A61N2/00
CPCA61N5/0601A61N5/062A61N5/0622A61N2/002A61N2/004A61N2/006A61F5/566A61B5/08A01K67/0275A61N2005/0626A61N2005/063A61N2005/0645A61N2005/0663A61C7/08A61M2202/206A01K2227/105A01K2267/03A61N5/067A61B5/296A61N5/0603A61N2005/0606C12N2750/14143A61N1/0452A61N1/0456
Inventor 琳妮·比尔斯顿彼得·伯克
Owner 琳妮比尔斯顿
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