Neuron discharge spike signal picking method and device and computer equipment

A discharge signal and spike signal technology, applied in the field of digital signal processing, can solve the problems of increased workload, statistical errors of neural signals, and increased signal extraction instability, and achieves strong robustness, improved accuracy, and accurate picking. Effect

Active Publication Date: 2021-03-12
南京畅享医疗科技有限公司
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Problems solved by technology

[0003] This method requires people to observe the signal threshold, which increases the workload, and because the threshold is artificially specified, it increases the instability of signal extraction; and this method can only pick out the neural discharge spikes wi

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  • Neuron discharge spike signal picking method and device and computer equipment
  • Neuron discharge spike signal picking method and device and computer equipment
  • Neuron discharge spike signal picking method and device and computer equipment

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[0050] In order to make the purpose, technical solution and advantages of the present application clearer, the present application will be further described in detail below in conjunction with the accompanying drawings and embodiments. It should be understood that the specific embodiments described here are only used to explain the present application, and are not intended to limit the present application.

[0051] In one embodiment, such as figure 1 As shown, a method for picking out neuron firing spikes is provided, comprising the following steps:

[0052] Step S220, performing preprocessing on the discharge signal of the neuron to be picked to obtain a continuous filtered discharge signal.

[0053] Wherein, the neuron discharge signal to be selected is a continuous original neuron discharge signal continuously collected by the neuron discharge signal acquisition device within a period of time. Preprocessing includes upsampling and filtering. The frequency range of neuron ...

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Abstract

The invention relates to a neuron discharge spike signal picking method and device, computer equipment and a storage medium. The method comprises the following steps: preprocessing a to-be-picked neuron discharge signal to obtain a continuous filtering discharge signal; performing energy calculation on the continuous filtering discharge signal to obtain a continuous energy signal; performing peakvalue statistics on the continuous energy signal to determine an energy peak value; establishing a cumulative distribution function of chi-square distribution according to the continuous energy signals for analysis, and determining a picking threshold; screening the energy peak values through a preliminary peak value extraction model constructed by the picking threshold value to obtain a preliminary peak value; extracting a signal segment in the continuous filtering discharge signal according to the preliminary peak value to obtain a discharge signal segment; and analyzing the discharge signalsegment according to the picking threshold, and determining a neuron discharge peak signal. Through the method, the robustness of picking the neuron discharge spike signals is stronger, and the accuracy of the picking result is also improved.

Description

technical field [0001] The present application relates to the technical field of digital signal processing, in particular to a method, device, computer equipment and storage medium for picking out neuron discharge spike signals. Background technique [0002] When collecting neural signals, a high sampling rate method is used to record the continuous signals around the neurons, and the neuron spike signal (Spike) is a short discharge process, lasting about 1ms. In order to extract this short-term signal, the commonly used method is to observe the signal, set a threshold, and select the signal that exceeds the threshold as a firing process of a neuron. [0003] This method requires people to observe the signal threshold, which increases the workload, and because the threshold is artificially specified, it increases the instability of signal extraction; and this method can only pick out the neural discharge spikes with large amplitudes. However, some spikes with smaller amplit...

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Application Information

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IPC IPC(8): A61B5/388A61B5/00G06F17/14G06F17/15G06F17/18
CPCA61B5/72G06F17/148G06F17/15G06F17/18
Inventor 吴正平魏欢熊灵艺
Owner 南京畅享医疗科技有限公司
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