A kudzu flower extract that promotes oral absorption of calcium
An extract and extraction technology of kudzu, applied in the fields of food and medicine, can solve the problems of low absorption efficiency of oral calcium tablets, high cost of calcium supplementation by injection, and low patient compliance.
Active Publication Date: 2022-04-08
益家元品实业(厦门)有限公司
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Problems solved by technology
Oral calcium tablets such as calcium carbonate tablets are commonly used calcium supplements. However, oral calcium tablets often have the problem of low absorption efficiency, especially for the elderly. Therefore, in order to supplement calcium, it is necessary to take large amounts of calcium tablets for a long time, causing patients Low compliance. In addition, for patients with severe calcium deficiency, calcium injections are often required due to the slow absorption rate of oral calcium tablets. However, the cost of injections of calcium supplements is high and patient compliance is low, so it is not suitable for patients with long-term calcium supplementation
There is a lack of drugs to promote oral absorption of calcium in the prior art, thus limiting the effective treatment of calcium deficiency by oral calcium tablets
Method used
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Embodiment 1
[0129] (1) Preparation of kudzu flower extract, kudzu flower extract is prepared by the following method:
[0130] (a) Weigh 50g of kudzu flower, add 400ml of 60% (v / v) ethanol aqueous solution after crushing, heat and reflux for extraction for 6h, filter, and concentrate the filtrate to 100ml under reduced pressure to obtain a concentrated solution;
[0131] (b) Extract the concentrated solution obtained in step (a) with 300mL petroleum ether each time, extract twice in total, combine the petroleum ether layers obtained by the two separations (i.e. petroleum ether extract), remove petroleum ether by distillation under reduced pressure, and dry , to obtain kudzu flower extract.
[0132] (2) Investigate the effect of the kudzu flower extract prepared in this embodiment on calcium absorption
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The invention relates to a Pueraria japonica extract for promoting oral absorption of calcium. Specifically, the present invention provides a kudzu flower extract, which is prepared by the following method: (1) extracting kudzu flower with an alcohol solvent to obtain an alcohol extract; (2) the alcohol extraction After the liquid is concentrated, an organic solvent is added for extraction, and the organic phase is distilled off under reduced pressure to obtain the kudzu flower extract, wherein the organic solvent includes one or more of petroleum ether, chloroform, and ethyl acetate. The kudzu flower extract of the invention can effectively promote oral absorption of calcium, improve blood calcium level, and treat calcium deficiency.
Description
technical field [0001] The invention relates to the fields of food and medicine, in particular to a kudzu flower extract for promoting oral absorption of calcium. Background technique [0002] Calcium is an important structural component in organisms and participates in the regulation of various physiological processes of cells. For example, the physiological functions of calcium in the human body include biological calcification in the body, blood coagulation, muscle contraction and nerve signal transmission, etc., so as to maintain normal physiology function. [0003] Calcium deficiency can cause various diseases, especially for infants, children and pregnant women, calcium deficiency often causes osteomalacia, convulsions, convulsions, back pain, joint pain and so on. Oral calcium tablets such as calcium carbonate tablets are commonly used calcium supplements. However, oral calcium tablets often have the problem of low absorption efficiency, especially for the elderly. T...
Claims
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IPC IPC(8): A61K36/488A61K31/593A61K33/10A61P3/14A23L33/105A23L33/155A23L33/16A23L2/52A23C9/13
CPCA61K36/488A61K31/593A61K33/10A61P3/14A23L33/105A23L33/155A23L33/16A23L2/52A23C9/13A23C9/1322A61K2236/333A61K2236/55A23V2002/00A61K2300/00A23V2300/14A23V2250/21A23V2200/30
Inventor 庄瑞宾王建智陈旭侯龙辉叶梓
Owner 益家元品实业(厦门)有限公司