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Antibacterial hemostatic hydrogel and preparation method thereof

A hydrogel and deionized water technology, applied in the medical field, can solve the problems of no literature and patent reports, long wound healing time, and easy infection, etc., to achieve good applicability, promote wound healing, and improve the health of the body. The effect of immune cell activity

Inactive Publication Date: 2021-03-16
王忠良
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0010] The above-mentioned liquid bandages contain non-natural volatile solvents and film-forming agents, which not only have a pungent smell, but also the waterproof film is not easy to fall off. It needs to be softened with a solvent. When it is peeled off, it will cause pain and even cause secondary damage due to bleeding.
Secondly, because the formed membrane is airtight, the wound will heal for a long time, and even prone to infection
The present invention uses hemicellulose and modified hemicellulose natural polysaccharides to prepare a bacteriostatic and hemostatic hydrogel on the basis of the above-mentioned patent application. Bacteriostatic components, hemostatic components and sealability, and high viscosity of soap kernel liquid gel synergistically prepare a kind of bacteriostatic hemostatic hydrogel. The compatibility and preparation method described in the present invention have no literature or patent reports.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0036] A bacteriostatic and hemostatic hydrogel consists of the following components in parts by weight: 3 parts of hemicellulose, 0.5 parts of modified hemicellulose, 2.5 parts of emulsified wood wax oil, 1.5 parts of sumac leaf extract, 0.5 part of fragrance leaf extract parts, 1.5 parts of soap kernel liquid, and 150 parts of deionized water.

[0037] A kind of preparation method of antibacterial hemostatic hydrogel in the present embodiment, comprises the following steps:

[0038] (1) First dissolve hemicellulose in solvent water according to the solid-to-liquid ratio of 1:40;

[0039] (2) Add the hemicellulose solution in the above step (1) to the modified hemicellulose and heat to dissolve at 80°C to form viscose and keep it warm for later use;

[0040] (3) Add emulsified wood wax oil, lacquer tree leaf extract, fragrance leaf extract, and soap kernel liquid to the viscose liquid in the above step (2), keep it warm at 40°C for 12 hours, and stir at the same time;

[00...

Embodiment 2

[0044] A bacteriostatic hemostatic hydrogel consists of the following components in parts by weight: 5 parts of hemicellulose, 1.5 parts of modified hemicellulose, 3.5 parts of emulsified wood wax oil, 2.5 parts of sumac leaf extract, 1.5 parts of fragrant leaf extract parts, 3.5 parts of soap kernel liquid, and 200 parts of deionized water.

[0045] A kind of preparation method of antibacterial hemostatic hydrogel in the present embodiment, comprises the following steps:

[0046] (1) Dissolve hemicellulose in solvent water at a solid-to-liquid ratio of 1:45;

[0047] (2) Add the hemicellulose solution in the above step (1) to the modified hemicellulose and heat it to 85°C for dissolving treatment to form viscose and keep it warm for later use;

[0048] (3) Add emulsified wood wax oil, sumac leaf extract, fragrance leaf extract, and soap kernel liquid to the viscose liquid in the above step (2), keep it warm at 45°C for 8 hours, and stir at the same time;

[0049] (4) Add de...

Embodiment 3

[0052] A bacteriostatic hemostatic hydrogel consists of the following components in parts by weight: 6 parts of hemicellulose, 2.5 parts of modified hemicellulose, 5.5 parts of emulsified wood wax oil, 4.5 parts of sumac leaf extract, 2.5 parts of fragrant leaf extract parts, 4.5 parts of soap kernel liquid, and 300 parts of deionized water.

[0053] The preparation method of a kind of antibacterial hemostatic hydrogel in the present embodiment comprises the following steps:

[0054] (1) Dissolve hemicellulose in solvent water at a solid-to-liquid ratio of 1:50 and dissolve completely;

[0055] (2) Add the hemicellulose solution in the above step (1) to the modified hemicellulose and heat it to 90°C for dissolving treatment to form viscose and keep it warm for later use;

[0056] (3) Add emulsified wood wax oil, lacquer leaf extract, fragrance leaf extract, and saponin liquid to the viscose liquid in the above step (2), keep it warm at 50°C for 6 hours, and stir at the same t...

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PUM

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Abstract

The invention discloses antibacterial hemostatic hydrogel and a preparation method thereof, and relates to the field of hydrogel and preparation thereof. The hydrogel is prepared from the following components in parts by weight: 3-8 parts of hemicellulose, 0.5-2.5 parts of modified hemicellulose, 0.5-2.5 parts of emulsified wax oil, 1.5-4.5 parts of a lacquer tree leaf extract, 0.5-2.5 parts of afaint scent leaf extract, 1.5-4.5 parts of soap kernel liquid and 50-100 parts of deionized water. The antibacterial hemostatic hydrogel has the advantages of good skin friendliness, high hydrophobicity, no need of viscose cloth, good air permeability, good hemostatic effect and good antibacterial property. The antibacterial hemostatic hydrogel is suitable for hemostasis and bacteriostasis of skintrauma, and is further suitable for auxiliary treatment of itching relieving, beriberi, chapping or eczema of skin, and auxiliary repair of skin injury surfaces of scalds, burns and the like.

Description

technical field [0001] The invention belongs to the field of medical technology, and in particular relates to a bacteriostatic and hemostatic hydrogel and a preparation method thereof. Background technique [0002] Trauma is the damage of normal skin under the joint action of external injury factors (external force, heat, surgery, electric current, chemical substances and low temperature, etc.) and internal factors of the body (local blood supply insufficiency). The appearance of wounds is generally accompanied by the destruction of skin integrity and the loss of some normal tissues, resulting in impairment of normal skin function. Wound repair is a complex process involving multiple cells and cytokines, and wound dressings play an important role in the process of healing and repairing wounds. When using a dressing to treat a wound, the dressing can isolate external microorganisms, avoid further infection of the wound, and then use its own healing and repairing ability to p...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L26/00
CPCA61L26/0023A61L26/0057A61L26/008A61L26/0066A61L26/0061A61L2300/30A61L2300/404A61L2300/418A61L2400/04C08L5/14
Inventor 王忠良
Owner 王忠良
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