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Composition for treating alopecia and preparation method thereof

A compound and hair loss technology, which is applied in the field of medicine, can solve the problems of high cost of hair transplantation and little effect, and achieve good therapeutic effect

Pending Publication Date: 2021-03-30
北京唐颐惠康生物医学技术有限公司 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] Alopecia is the phenomenon of hair loss, which can be divided into physiological and pathological points. Physiological alopecia refers to normal hair loss, and pathological alopecia refers to abnormal or excessive hair loss. With the increasing social pressure and the faster pace of life , changes in eating habits and other reasons, there are more and more hair loss patients at home and abroad. Although there are various medicines for the treatment of hair loss on the market, most of them have little effect. Some patients choose to have hair transplantation, but hair transplantation higher cost

Method used

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  • Composition for treating alopecia and preparation method thereof
  • Composition for treating alopecia and preparation method thereof
  • Composition for treating alopecia and preparation method thereof

Examples

Experimental program
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Effect test

Embodiment 1

[0048] A compound for treating hair loss, the compound is prepared from botulinum toxin and umbilical cord mesenchymal stem cells, and the preparation method is as follows:

[0049] S1 Preparation of the first preparation unit: Use physiological saline containing 1% human serum albumin to prepare a concentration of 5×10 6 cell / ml umbilical cord mesenchymal stem cell suspension 1L;

[0050] S2 preparation of the second preparation unit: using physiological saline to prepare 1 L of botulinum toxin solution with a concentration of 10 U / ml;

[0051] S3: uniformly mix the first preparation unit and the second preparation unit at a ratio of 1:1 to obtain the compound;

[0052] The botulinum toxin used in the present invention is all botulinum toxin type A for injection, purchased from Allergan, the product number is 92949CH, and the batch number is S20171005. The sources of umbilical cord mesenchymal stem cells in all the examples of this application are commercially available.

Embodiment 2

[0054] A compound for treating hair loss, the compound is prepared from botulinum toxin and umbilical cord mesenchymal stem cells, and the preparation method is as follows:

[0055] S1 Preparation of the first preparation unit: Use physiological saline containing 1% human serum albumin to prepare a concentration of 1×10 6 cell / ml umbilical cord mesenchymal stem cell suspension 1L;

[0056] S2 preparation of the second preparation unit: using physiological saline to prepare 1 L of botulinum toxin solution with a concentration of 10 U / ml;

[0057] S3: Mix the first preparation unit and the second preparation unit uniformly at a ratio of 1:1 to obtain a compound.

Embodiment 3

[0059] A compound for treating hair loss, the compound is prepared from botulinum toxin and umbilical cord mesenchymal stem cells, and the preparation method is as follows:

[0060] S1 Preparation of the first preparation unit: Use physiological saline containing 1% human serum albumin to prepare a concentration of 2×10 5 cell / ml umbilical cord mesenchymal stem cell suspension 1L;

[0061] S2 preparation of the second preparation unit: using physiological saline to prepare 1 L of botulinum toxin solution with a concentration of 10 U / ml;

[0062] S3: Mix the first preparation unit and the second preparation unit uniformly at a ratio of 1:1 to obtain a compound.

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Abstract

The invention provides a composition for treating alopecia, the composition is prepared from botulinum toxin and mesenchymal stem cells, and the dosage ratio of the botulinum toxin to the mesenchymalstem cells is 10U: 2-50 * 105; the composition for treating alopecia can be used for effectively treating alopecia and has a good treatment effect.

Description

technical field [0001] The invention belongs to the technical field of medicine, and in particular relates to a compound for treating hair loss and a preparation method thereof. Background technique [0002] Alopecia is the phenomenon of hair loss, which can be divided into physiological and pathological points. Physiological alopecia refers to normal hair loss, and pathological alopecia refers to abnormal or excessive hair loss. With the increasing social pressure and the faster pace of life , changes in eating habits and other reasons, there are more and more hair loss patients at home and abroad. Although there are various medicines for the treatment of hair loss on the market, most of them have little effect. Some patients choose to have hair transplantation, but hair transplantation The cost is higher. Contents of the invention [0003] In order to solve the above technical problems, the present invention provides a compound for treating hair loss, the active ingredi...

Claims

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Application Information

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IPC IPC(8): A61K38/16A61K35/28A61K9/08A61K9/10A61P17/14
CPCA61K38/164A61K35/28A61K9/08A61K9/10A61P17/14A61K2300/00
Inventor 张海林付丹丹曹毓琳滕睿頔田中伟
Owner 北京唐颐惠康生物医学技术有限公司
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