Prediction model for inhalation pneumonia of patient suffering from radiation posterior cranial nerve paralysis and construction method of prediction model

A technique for paralyzing patients and cranial nerves, applied to the prediction model of aspiration pneumonia in patients with cranial nerve palsy after radiation group and its construction field, can solve problems such as inconvenience, and achieve the effects of simple model model, less error in judgment, and good survival benefit.

Inactive Publication Date: 2021-04-09
SUN YAT SEN MEMORIAL HOSPITAL SUN YAT SEN UNIV
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However, the validity period of the nasogastric feeding tube is 1 month, and repeated replacement of the gastric tube brings great inconvenience

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  • Prediction model for inhalation pneumonia of patient suffering from radiation posterior cranial nerve paralysis and construction method of prediction model
  • Prediction model for inhalation pneumonia of patient suffering from radiation posterior cranial nerve paralysis and construction method of prediction model
  • Prediction model for inhalation pneumonia of patient suffering from radiation posterior cranial nerve paralysis and construction method of prediction model

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Embodiment 1

[0027]1, case choice and classification

[0028]The inventors collected from January to January 2018 in the diagnosis of patients with radiotherapy after nasopharyngeal carcarcota in a certain hospital. The diagnostic criteria of LCNP refer to the research of previous reports. Simply put, the diagnosis of LCNP caused by radiotherapy is based on careful physical examination, detailed medical history, and LCNP caused by other reasons except for radiation. Take the LCNP caused by tumor recurrence by Mirror mirror, MRI or PET-CT. In addition, careful follow-up ≥12 months were performed before the LCNP caused by radiotherapy. Incorporate standard: (a) age ≥ 18 years old; (b) Nasopharyngeal carcinoma; (c) Evidence of LCNP. Exclusion criteria: (a) Nasopharyngeal carcinoma metastasis; (b) has evidence that LCNP has nothing to do with radiotherapy. These eligible patients are randomly divided into training queues and verification queues.

[0029]According to the above screening criteria, 453 patie...

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Abstract

The invention provides a method for constructing an inhaled pneumonia risk prediction model of a patient suffering from radiation posterior cranial nerve paralysis. The method comprises the following steps: S1, collecting clinical characteristic data of a patient diagnosed as a patient suffering from radiation-induced posterior cranial nerve paralysis after nasopharyngeal carcinoma radiotherapy; s2, performing survival correlation analysis on the clinical characteristic data and the total lifetime of the patient through a COX regression model to obtain clinical characteristics related to post-radiotherapy cranial nerve paralysis; and S3, constructing a line graph model for predicting the risk of the inhalation pneumonia of the patient suffering from the post-radiation cranial nerve paralysis by using the clinical features screened in the step S2.

Description

Technical field[0001]The present invention belongs to the field of biotherapeutic, and in particular, the present invention relates to an inhaled pneumonia prediction model and its construction method thereof.Background technique[0002]After the endogenous obstruction (LCNP), the brain nerve IX, X, XI and XII, affecting the function of swallowing, taste, breathing, and speaking. Radiotherapy-induced LCNP occurs in patients with nasopharyngeal carcinoma, mainly due to dysphagia, often causes severe pneumonia in patients with 5.7-37.3% nasopharyngeality After radiotherapy, the swallowing function continued to deteriorate over time, suggesting an increase in the risk of inhaled pneumonia. Radiation therapy of patients with swallowing difficulties Related inhaled pneumonia is twice as many patients with non-swallowing difficulties.[0003]The effects of inhaled pneumonia are quite large. On the one hand, inhalation pneumonia needs to support the ICU, extended hospitalization, seriously aff...

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G16H50/50G16H50/30
CPCG16H50/30G16H50/50
Inventor 唐亚梅李红红李艺容小明何蕾徐永腾蔡锦华
Owner SUN YAT SEN MEMORIAL HOSPITAL SUN YAT SEN UNIV
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