Composition for preventing and treating alcoholic liver injury and its preparation method and application
A technology for alcohol-induced liver injury and a composition, applied in the field of biomedicine, can solve problems such as single, unstable action pathway of antioxidant active substances, and achieve the effects of simple preparation process, improved physical properties and taste, and no bad smell
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[0051] As another aspect of the present invention, this embodiment also provides a method for preparing the above-mentioned composition for preventing and treating alcoholic liver injury, comprising the following steps:
[0052] S1. Take sodium alginate and add water to prepare sodium alginate solution, adjust the pH of the solution to 6.0-7.5, add spermidine, stir at room temperature for 5-8 hours, treat in ice water bath, wait for the solution system to cool down to 5-10°C, add seaweed Polyphenols, continue to stir for 1-3 hours, freeze-dry, and crush with liquid nitrogen to obtain seaweed polyphenol composite powder;
[0053] S2. Dissolving the abalone peptide with water to prepare an abalone peptide solution, adding the seaweed polyphenol composite powder under stirring, suspending evenly, and freeze-drying to obtain the composition for preventing and treating alcoholic liver injury.
[0054] During the preparation process of the composition for preventing and treating alc...
Embodiment 1
[0061] A composition for preventing and treating alcoholic liver injury comprises the following components in parts by weight: 20 parts of seaweed polyphenol, 4 parts of sodium alginate, 40 parts of abalone peptide and 1.5 parts of spermidine.
[0062] The preparation method of described composition comprises the following steps:
[0063] S1. According to the parts by weight, take sodium alginate and add distilled water to prepare a 1.5wt% sodium alginate solution, adjust the pH of the solution to 6.5, add spermidine, stir at room temperature for 6.5 hours, treat in an ice-water bath, and wait for the solution system to cool down to At 8°C, add seaweed polyphenols, continue to stir for 2 hours, freeze-dry, and crush with liquid nitrogen to obtain seaweed polyphenols composite powder;
[0064] S2. Dissolve the abalone peptide in distilled water to prepare a 22wt% abalone peptide solution, add the seaweed polyphenol composite powder described in S1 under stirring, suspend evenly...
Embodiment 2
[0066] A composition for preventing and treating alcoholic liver injury comprises the following components in parts by weight: 15 parts of seaweed polyphenol, 3 parts of sodium alginate, 35 parts of abalone peptide and 1 part of spermidine.
[0067] The preparation method of described composition comprises the following steps:
[0068] S1. According to the parts by weight, take sodium alginate and add distilled water to prepare 2.0wt% sodium alginate solution, adjust the pH of the solution to 7.0, add spermidine, stir at room temperature for 7 hours, treat in an ice-water bath, and wait for the solution system to cool down to At 6°C, add seaweed polyphenols, continue to stir for 1.5 hours, freeze-dry, and crush with liquid nitrogen to obtain seaweed polyphenols composite powder;
[0069] S2. Dissolve the abalone peptide in distilled water to prepare a 24wt% abalone peptide solution according to the parts by weight, add the seaweed polyphenol composite powder described in S1 un...
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