Universal rapid micro-mixer based on surface curing three-dimensional printing

Abstract

The invention relates to a universal rapid micro-mixer based on surface curing three-dimensional printing. The micro-mixer comprises a shell, wherein a liquid inlet module, a straight micro-channel module, a double-spiral micro-channel module and a mixed liquid outlet module are integrated in the shell; the liquid inlet module comprises at least two inlets used for inputting liquids with different concentrations; an inlet and an outlet of the straight micro-channel module are connected with an outlet of the liquid inlet module and an inlet of the double-spiral micro-channel module respectively to form a passage, and an outlet of the double-spiral micro-channel module is connected with an inlet of the mixed liquid outlet module to form a passage; the straight micro-channel module is provided with a straight micro-channel cavity, and several first obstacles are distributed in the straight micro-channel cavity; and the double-spiral micro-channel module comprises an inflow spiral section and an outflow spiral section, wherein the spiral sections are composed of a plurality of expansion and contraction flow channels with periodically-changed sectional areas, and several second obstacles are distributed in the expansion and contraction flow channels. According to the micro-mixer, the contact area and the mixing length of the liquids with different concentrations are increased, and a good mixing effect is achieved for fluids with different reynolds numbers.

Description

technical field [0001] The invention relates to the field of microfluidic technology, in particular to a universal fast micro-mixer based on surface solidification 3D printing. Background technique [0002] Microfluidics plays an increasingly important role in biochips and lab-on-a-chip. When two or more fluids undergo chemical reactions, it is necessary to solve the effective mixing of fluids. Therefore, micromixers are an important part of microfluidic systems. component. Due to the small size of the channel structure of the micro-mixer, usually on the micron scale, plus the Reynolds number of the fluid (Reynolds number, which is the ratio between the inertial force and the viscous force when the fluid flows, it is usually a standard for judging the fluid flow state , when the Reynolds number is larger, the dominant effect of the inertial force in the fluid is greater, and when the Reynolds number is smaller, the dominant effect of the viscous force in the fluid is greate...

AI Technical Summary

Problems solved by technology

[0003] In the prior art, most of the micro-mixers can achieve the mixing purpose within a single Reynolds number range. For example, the straight channel has a better mixing effect at a low Reynolds number state, and the spiral flow has a better mixing effect at a high Reynolds number state. This makes Micromixers have limited versatility

Moreover, for a single microfluidic channel structure, such as a straight channel, the mixing process is relatively slow, and external power supply is required to overcome the huge loss of system pressure, resulting in the weakening or even disappearing of the advantages of fast microfluidic analysis.

[0004] With the rapid development of 3D printing technology, the printing accuracy is getting higher and higher, especially based on surface curing 3D printing, the processing format is large, and the accuracy can reach 5 microns. The processing of flow channel structure with multi-layer complex cross-section is helpful to realize the fine design of micro-channel size structure. At present, there is still a lack of related products to meet the rapid mixing performance of fluids at the micro-scale

Images