Multi-parameter brain function measuring method and device

Abstract

The invention discloses a multi-parameter brain function measuring method and device. The device includes a source measurement fixing unit, a light source unit, a monitoring unit, a collection unit, a correlation operation unit and a control and memory unit. The near infrared light of the light source unit is transmitted through multimode fiber to expose on a scalp; photonic signals emitted after passing through the brain is received by single mode fiber, and the photonic signals transmitted to the collection unit are integrated, so that analog-to-electrical conversion can be performed; the correlation operation unit obtains light intensity autocorrelation function from light intensity sequence signals through an autocorrelation based method; and the control and memory unit calculates cerebral blood flow indexes, cerebral blood volume indexes and respective functional connectivity in a preset relative optical density algorithm model, light intensity autocorrelation function fitting algorithm model and Pearson related algorithm model. Through the method and device, functions such as multi-channel and multi-parameter brain function measurement can be realized; and the device can comprehensively reflect the characteristics of cerebral hemodynamics and has the advantages of being low in cost, high in sensitivity and portable in carrying.

Description

technical field [0001] The invention relates to the field of hemodynamic measurement, in particular to a method and device for measuring brain function. Background technique [0002] Cerebral hemodynamic parameters include cerebral blood flow, cerebral blood volume, etc. These parameters can reflect neural activity from different aspects and provide rich information on changes in brain physiological functions. The measurement of brain function parameters such as cerebral blood flow and blood volume has important reference value for early diagnosis and early intervention of clinically relevant brain diseases. Cerebral blood volume can directly characterize the blood perfusion and vasomotor activity (vasodilation / constriction) of local tissues, which is of great significance for the evaluation of diseases such as brain injury [1-3] . Cerebral blood volume can be measured using near-infrared spectroscopy, a noninvasive method that estimates cerebral blood volume and cerebral ...

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