The invention discloses an intelligent operation inspection system and method for power transmission equipment, and the system comprises an operation inspection terminal, an intelligent operation inspection monitoring gateway, an intelligent operation inspection center station, an electric power overhead optical cable, and a plurality of control towers. The intelligent operation inspection center station comprises a laser, a first modulator, an electric signal source, and an analog-to-digital conversion module, and a first polarization analyzer, a first circulator, a second polarization analyzer, a demodulator and an optical detector. The control tower comprises a first micro-ring, a second micro-ring, a third micro-ring, a second circulator, a third circulator, a second modulator and a third modulator, the input end of the second modulator is connected with a first GPS antenna, the input end of the third modulator is connected with a second GPS antenna, and the third micro-ring is connected with a Sagnac reflector. The system is simple in structure, combined with an operation and maintenance method, can be effectively applied to operation and maintenance of the power transmission equipment, improves the operation and maintenance efficiency, is high in anti-electromagnetic interference capability, is suitable for working conditions with complex electromagnetic environments in the power transmission equipment, is remarkable in effect, and is convenient to popularize.