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Compound paclitaxel anti-tuberculosis capsule tablet preparation method and process

A production method, paclitaxel technology, applied in the direction of antibacterial drugs, microcapsules, capsule delivery, etc., can solve the problems of reducing the drug safety of tuberculosis patients, the treatment effect of tuberculosis is not significant enough, and the liver damage of patients, etc., to improve the overall Defense function, protection of normal cells, high curative effect

Pending Publication Date: 2021-07-13
庞中龙
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Problems solved by technology

[0003] At present, when the anti-tuberculosis drugs on the market are used to treat tuberculosis, they not only take effect slowly, but the therapeutic effect is not significant enough, and the drugs have relatively large toxic and side effects after use, which is easy to cause damage to the liver of patients, which greatly reduces the risk of tuberculosis patients. Medication safety and efficacy of tuberculosis treatment

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  • Compound paclitaxel anti-tuberculosis capsule tablet preparation method and process

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Embodiment Construction

[0021] Compound paclitaxel anti-tuberculosis capsule preparation method and process, compound paclitaxel anti-tuberculosis capsule preparation method and process, it comprises the following steps:

[0022] Step 1: Take quantitative paclitaxel extract for dilution, and separate and passivate the diluted paclitaxel extract;

[0023] Step 2: eluting the paclitaxel extract after separation and passivation, and recovering and concentrating the eluted paclitaxel;

[0024] Step 3: Vacuum-dry the recovered and concentrated paclitaxel extract, and pulverize the dried crystals to prepare the finished raw material medicine for future use;

[0025] Step 4: adding traditional Chinese medicine auxiliary materials to the finished raw material medicine prepared in step 3, stirring, pulverizing and filtering, so as to prepare a mixed raw medicine for later use;

[0026] Step 5: making granular pills from the crushed and filtered mixed bulk drug on a granulator, and vacuum-drying the pills;

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Abstract

The invention discloses a compound paclitaxel anti-tuberculosis capsule tablet preparation method and process, and the process comprises the following steps: step 1, taking a certain amount of paclitaxel extract for dilution, and carrying out separation and passivation treatment on the diluted paclitaxel extract; step 2, carrying out elution treatment on the separated and passivated paclitaxel extract, and carrying out recovery and concentration on the eluted paclitaxel. The paclitaxel anti-tuberculosis capsule tablet has the beneficial effects that the prepared paclitaxel anti-tuberculosis capsule tablet directly kills tubercle bacillus and cancer cell tissues by adopting toxic attack, protects normal cells, is free of toxic reaction, high in curative effect, short in medication time, free of damage to the liver. Meanwhile, the paclitaxel anti-tuberculosis capsule tablet can stimulate and adjust the immune defense function in vivo, enhance the digestion and absorption functions and improve the overall defense function while treating, so that the treatment of tuberculosis is more efficient and safer.

Description

technical field [0001] The invention relates to the technical field of drugs for treating tuberculosis, in particular to a method and process for preparing compound paclitaxel anti-tuberculosis capsule tablets. Background technique [0002] Tuberculosis is a chronic infectious disease caused by Mycobacterium tuberculosis, which can invade many organs, and pulmonary tuberculosis is the most common form of lung involvement. Tuberculosis is not only an ancient disease, but also an urgent public health and social problem facing the world. It is estimated that nearly 2 billion people worldwide are infected with tuberculosis, accounting for 1 / 3 of the global population. Of these, 20 million suffer from active tuberculosis. There are 10 million new cases every year in the world, and 3 million people die of tuberculosis every year. According to relevant persons from WHO, the number of tuberculosis patients will increase to more than 30 million in the next 10 years, and the use of...

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/904A61K31/337A61K9/48A61P31/06A61P35/00A61P37/04
CPCA61K31/337A61K36/258A61K36/481A61K36/536A61K36/185A61K36/898A61K36/904A61K36/8945A61K36/484A61K36/725A61K9/5084A61P31/06A61P35/00A61P37/04A61K2300/00
Inventor 庞作仁李恩荣杨贵修王明会刘东庞中龙杨忠荣
Owner 庞中龙
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