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Compositions comprising polar lipids for maintaining or increasing mobility and vitality

A technology of polar lipids and compositions, which can be used in drug combinations, organic active ingredients, food ingredients containing oil, etc., and can solve problems such as loss of functional decline and lack of muscle.

Pending Publication Date: 2021-11-05
FONTERRA COOP GRP LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Currently, there are no agents available to prevent muscle loss or functional decline

Method used

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  • Compositions comprising polar lipids for maintaining or increasing mobility and vitality
  • Compositions comprising polar lipids for maintaining or increasing mobility and vitality
  • Compositions comprising polar lipids for maintaining or increasing mobility and vitality

Examples

Experimental program
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Effect test

example

[0404] The purpose of this example was to study the effect of administration of a composition comprising polar lipids on mobility and vitality.

[0405] 1. Method

[0406] 244 middle-aged sedentary women were recruited. Exclusion criteria include: 1) Age 65; 2) BMI 2 or >40kg / m 2 ; 3) In the past 6 months, are or have participated in resistance exercise (> 1 week) and / or engaged in moderate-intensity physical activity ≥ 150 minutes per week; 4) If the sedentary time of adults in the past day (Past-day Adults 'Sedentarytime, PAST) scale (Clark et al. Med Sci Sports Exerc. [Sports Training Medicine and Science] 2013 45(6):1198207) measured daily sedentary time 900 mg; 6) Regular (> 3 times per week) use of anti-inflammatory drugs (including aspirin, ibuprofen, omega 3 supplements / fish oil) in the past 3 months; 7) Use of oral hormone replacement therapy in the past 12 months; 8) Osteoporosis or any low-trauma fracture in the past 12 months; 9) Any other metabolic bone disease...

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PUM

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Abstract

The present invention provides methods of maintaining or increasing mobility and / or vitality, in particular for middle-aged, sedentary women, by administering a composition comprising one or more polar lipids, such as milk fat globule membrane, whey and other dairy products.

Description

technical field [0001] The present invention relates to the use of polar lipids, in particular polar lipids derived from milk, to maintain or increase mobility and vitality. Also provided are methods for using polar lipids and compositions comprising polar lipids. Background technique [0002] Muscle mass, strength, function and power begin to gradually decline at about 40 to 45 years of age and accelerate in the second half of life (Doherty. J Appl Physiol [Journal of Applied Physiology] (1985). 2003 Oct; 95(4): 1717-27 ; Janssen et al. J Appl Physiol (1985). 2000 Jul.; 89(1):81-8; Lindle et al. J Appl Physiol (1985). Nov. 1997; 83(5):1581-7). Clinically, age-related muscle loss is noteworthy because it is associated with impaired mobility and vitality and is associated with an increased risk of falls, fractures, and other common chronic metabolic diseases (Fielding et al, J Am Med Dir Assoc. [Journal of American Academy of Medical Directors] 2011 May;12(4):24956; Cruz-J...

Claims

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Application Information

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IPC IPC(8): A61K31/164A61K31/688A61K31/683A61P19/10A61P21/06A61P3/04A61P43/00
CPCA61K31/688A61K31/685A61K31/683A61P19/10A61P21/06A61P3/04A61P43/00A61K31/593A61K33/06A61K31/164A23L33/40A23L33/10A23V2002/00A61K2300/00A23V2200/31A23V2250/18A61K31/7036A23L2/38A23P10/20A23V2200/33A23L33/115A23L2/52A61K31/661A61K31/7032
Inventor C·S·诺里斯亚伦·加尔文·范宁C·A·冈恩琳达·梅·斯谷鲁姆A·K·H·麦克吉本
Owner FONTERRA COOP GRP LTD
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