Hydrogel dressing for skin repair and preparation method thereof

A skin repair and hydrogel technology, applied in the field of cosmetic medicine, can solve the problems of insignificant repair effect, weak targeting of skin damage factors, singleness, etc., to improve the ability to resist external stimuli, regulate the immune function of the body, reduce the damage effect

Pending Publication Date: 2022-03-22
SHANGHAI NAT ENG RES CENT FORNANOTECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Because it is not very specific or relatively single to the factors that cause skin damage, the repair effect is not obvious

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] A kind of aqueous gel dressing for skin repair, prepared according to the following steps:

[0023] Add 1.2 g of thickener hydroxyethyl cellulose, 8 g of humectant hyaluronic acid, 8 g of trehalose, 0.1 g of preservative methyl paraben, and 0.1 g of chelating agent disodium edetate into 82.6 g of water and stir Obtain the solution evenly; then, heat the above solution to 70°C for 30 minutes;

[0024] After cooling down to 50°C, add 0.2 g of neutralizing agent aminomethyl propanol and neutralizing agent and stir to cool down to 48°C;

[0025] Add 1.5 g of β-glucan, continue stirring to 25° C., add 1.5 g of cytokine solution, and stir evenly to prepare the hydrogel.

Embodiment 2

[0027] A kind of aqueous gel dressing that is used for skin repair, is similar to embodiment 1 step, is prepared according to the following steps:

[0028] Add 1.2 g of thickener hydroxyethyl cellulose, 8 g of humectant lecithin, 8 g of trehalose, 0.1 g of preservative methyl paraben, and 0.1 g of chelating agent disodium edetate into 82.6 g of water and stir well solution; then,

[0029] Heat the above solution to 70°C for 30 minutes;

[0030] After cooling down to 50°C, add 0.2 g of neutralizing agent and stir to cool down to 48°C;

[0031] Add 2.5 g of β-glucan, continue stirring to 25° C., add 2.5 g of cytokine solution, and stir evenly to prepare the hydrogel.

Embodiment 3

[0033] A kind of aqueous gel dressing that is used for skin repair, is similar to embodiment 1 step, is prepared according to the following steps:

[0034] Add 1.2 g thickener hydroxyethyl cellulose, 8 g humectant lecithin and hyaluronic acid mixture, 8 g trehalose, 0.1 g preservative methyl paraben, 0.1 g chelating agent disodium edetate 82.6 g of water was stirred uniformly to obtain a solution; then,

[0035] Heat the above solution to 70°C for 30 minutes;

[0036] After cooling down to 50°C, add 0.2 g of neutralizing agent and stir to cool down to 48°C;

[0037] Add 3.5 g of β-glucan, continue stirring to 25° C., add 3.5 g of cytokine solution, and stir evenly to prepare the hydrogel.

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PUM

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Abstract

The invention discloses a hydrogel dressing for skin repair and a preparation method of the hydrogel dressing. The hydrogel dressing is prepared from the following components: beta-glucan, cell factors, trehalose, a thickening agent, a humectant, a preservative, a chelating agent, a neutralizer and water. The cleaning agent is non-toxic, harmless and non-irritant; through the synergistic effect of all the active substances, the moisturizing effect is good, the skin repairing effect of all the active ingredients is improved, and the after-sun repairing effect is better.

Description

technical field [0001] The invention relates to the technical field of aesthetic medicine, in particular to a hydrogel dressing for skin repair and a preparation method thereof. Background technique [0002] The skin is the largest organ of the human body. It is the first line of defense of the human body and covers the whole body. It not only has defensive protection, regulates body temperature, absorbs, secretes, excretes, participates in metabolism and immunity and other very important physiological functions. So skin injury and damage is a complex physiological process. With the extension of human life span, more and more people pay more attention to the performance of skin damage, such as dry and rough skin, redness and blackness after sun exposure, deepening wrinkles, weakened elasticity, and sagging. The most important cell component in the dermis of the skin is fibroblasts, whose number reduction, shape change, secretion and synthesis function weakening or decline a...

Claims

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Application Information

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IPC IPC(8): A61L26/00A61K8/73A61K8/55A61K8/60A61K8/64A61K8/04A61Q19/00
CPCA61L26/008A61L26/0066A61L26/0023A61L26/0047A61K8/731A61K8/553A61K8/735A61K8/60A61K8/73A61K8/64A61K8/042A61Q19/004A61L2300/412A61L2300/252A61L2300/41A61K2800/48C08L1/284C08L5/00C08L5/08C08L89/00
Inventor 崔大祥沈琦梁辉彭家伟张文桦高昂周诚
Owner SHANGHAI NAT ENG RES CENT FORNANOTECH
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