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Traditional Chinese medicine composition for protecting stomach, preparation method and preparation containing traditional Chinese medicine composition

A pharmaceutical preparation and composition technology, which is applied in the field of preparation of drugs for the treatment of gastric mucosal injury, can solve problems such as the troublesome preparation and medication process of Chinese patent medicines, limited gastric mucosal injury drugs or methods, and the inability to achieve overall conditioning, etc., to achieve Improves acute gastric mucosal injury, has a good effect of protecting the stomach, and has the effect of simple composition

Pending Publication Date: 2022-05-31
GANNAN MEDICAL UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] After years of research, humans have developed a variety of drugs or methods for the treatment of digestive system diseases, but the drugs or methods for the treatment of gastric mucosal damage are still very limited
Modern medicine mainly uses H2 receptor antagonists, proton pump inhibitors, anti-Helicobacter pylori drugs, gastric motility drugs, gastric mucosal protective agents, etc. to treat gastric mucosal injuries. Side effects such as nausea, constipation, etc., and easy to relapse, unable to achieve overall conditioning and prevent recurrence, resulting in high treatment costs
In terms of overall conditioning, traditional Chinese medicine has a unique curative effect, less adverse reactions, and affordable prices, and has been favored by more and more patients and medical staff. However, the current stomach-protecting traditional Chinese medicine has too complicated ingredients. The process is more troublesome, resulting in higher cost, and the drug effect is still relatively weak

Method used

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  • Traditional Chinese medicine composition for protecting stomach, preparation method and preparation containing traditional Chinese medicine composition
  • Traditional Chinese medicine composition for protecting stomach, preparation method and preparation containing traditional Chinese medicine composition
  • Traditional Chinese medicine composition for protecting stomach, preparation method and preparation containing traditional Chinese medicine composition

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0043] Add 1g of tangerine peel extract and 4g of woody extract to 100g of seabuckthorn tea oil mixture;

[0044] Among them, seabuckthorn tea oil mixed oil is obtained by mixing seabuckthorn extract and tea oil at a ratio of 1:1, woody extract, tangerine peel extract, and seabuckthorn extract 2 Extraction, extraction conditions: each extraction is 2 hours, the operating pressure is 25Mpa, the operating temperature is 35°C, extract twice, and combine the extracts.

Embodiment 2

[0046] In the present embodiment, except the added amount of tangerine peel extract and woody extract, all the other process conditions are the same as in Example 1, specifically:

[0047] Add 2.5g of tangerine peel extract and 2.5g of woody extract to 100g of seabuckthorn tea oil mixed oil to get it;

[0048] Among them, seabuckthorn tea oil mixed oil is obtained by mixing seabuckthorn extract and tea oil at a ratio of 1:1, woody extract, tangerine peel extract, and seabuckthorn extract 2 Extraction, extraction conditions: each extraction is 2 hours, the operating pressure is 25Mpa, the operating temperature is 35°C, extract twice, and combine the extracts.

Embodiment 3

[0050] In this implementation, except the added amount of tangerine peel extract and woody extract, all the other process conditions are the same as in Example 1, specifically:

[0051] Add 4g of tangerine peel extract and 1g of woody extract to 100g of seabuckthorn tea oil mixture;

[0052] Among them, seabuckthorn tea oil mixed oil is obtained by mixing seabuckthorn extract and tea oil at a ratio of 1:1, woody extract, tangerine peel extract, and seabuckthorn extract 2 Extraction, extraction conditions: each extraction is 2 hours, the operating pressure is 25Mpa, the operating temperature is 35°C, extract twice, and combine the extracts.

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Abstract

The invention discloses a traditional Chinese medicine composition for protecting the stomach, a preparation method and a preparation containing the traditional Chinese medicine composition. The traditional Chinese medicine composition is prepared from, by mass, 75-98 parts of sea-buckthorn and tea oil mixed oil, 1-15 parts of pericarpium citri reticulatae extract and 1-15 parts of radix aucklandiae extract, and the mass ratio of the sea-buckthorn extract to tea oil in the sea-buckthorn and tea oil mixed oil is 1: 2-2: 1. The traditional Chinese medicinal materials and the tea oil are fully adopted in the formula, the adverse reaction is few, the pericarpium citri reticulatae extract, the radix aucklandiae extract, the sea-buckthorn extract and the tea oil are reasonably combined, the stomach protection effect is good, acute gastric mucosal injury can be remarkably improved, overall conditioning and recurrence prevention are achieved, the traditional Chinese medicinal materials used in the formula are few in variety and simple in component, and the traditional Chinese medicinal composition is suitable for large-scale popularization and application. The tea oil is also one of daily edible vegetable oil, so that the tea oil is convenient and simple to prepare, and the cost of the tea oil is relatively low.

Description

technical field [0001] The invention relates to the technical field of medicine preparation, in particular to a traditional Chinese medicine composition for protecting the stomach and a preparation method, a preparation containing the traditional Chinese medicine composition, and an application of the traditional Chinese medicine composition in preparing medicine for treating gastric mucosal injury. Background technique [0002] Gastric mucosa is the outermost layer of the gastric mucosa, which is an important physiological barrier of the stomach and has a good protective effect on the stomach. Gastric mucosal injury is the first stage of a variety of gastrointestinal diseases. Depending on the severity of the injury, different symptoms are also manifested. Gastric mucosal damage may cause stomach pain, hematemesis, blood in the stool, ulcers, perforation, and a small number of ulcers may even develop into precancerous lesions and gastric cancer. Long-term and repeated atta...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/82A61K36/9068A61K9/20A61P1/00
CPCA61K36/185A61K36/82A61K36/752A61K36/285A61P1/00A61K36/9068A61K9/2031A61K2236/331A61K2236/333A61K2236/37A61K2300/00Y02A50/30
Inventor 范小娜范平龙李洪亮丁冶春肖海李林福谢树春
Owner GANNAN MEDICAL UNIV
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