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Medicine composition for treating ischemic necrosis of femur head and preparing process thereof

A technology of ischemic necrosis and composition, which is applied in the direction of drug combination, pharmaceutical formula, medical preparations containing active ingredients, etc., which can solve the problems of inconvenient taking, failure to achieve therapeutic effect, difficult to effectively maintain the course of treatment, etc., and achieve convenience in taking , Imaging performance improvement, and the effect of improving hip pain

Inactive Publication Date: 2005-06-15
吴振平
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Most of the unilateral prescriptions used are decoctions, which are inconvenient for patients to take, so the course of treatment is difficult to effectively maintain and thus the therapeutic effect cannot be achieved

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0082] To prepare 1000 medicinal capsules of the present invention, the required crude drugs Danshen 240g, Angelica 240g, Tuyuan 96g, Psoralen 120g, Leech 120g, Astragalus 240g, Speranthema 120g, natural copper 240g, Eucommia 160g, Sanqi 80g, Cinnamon 144g.

[0083] 1. Take notoginseng and cinnamon, crush them, pass through a 60-mesh sieve, and set aside;

[0084] 2. Take Salvia miltiorrhiza, extract with 8 times the amount of ethanol under reflux for 2 hours, filter, recover ethanol from the filtrate and concentrate under reduced pressure to a relative density of 1.30 (55°C-60°C) for later use;

[0085] 3. Get the medicinal residues of Salvia miltiorrhiza under item 2, add angelica, psoraleae, soil element, leech, reflux extraction with 8 times 50% ethanol for 3 hours, filter, reclaim ethanol from the filtrate and concentrate under reduced pressure until the phase density is 1.30 (55 ℃-60℃) for standby;

[0086] 4. Take the dregs of the 3 items, add the remaining medicinal ...

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Abstract

The invention discloses a pharmaceutical composition for treating avascular necrosis of the femoral head and a preparation method thereof. Composed of the following raw materials: Danshen, Angelica, Psoraleae, Leech, Tuyuan, Astragalus, Speranthema, Natural Copper, Eucommia, Panax notoginseng, and Cinnamon. Ethanol extraction of salvia miltiorrhiza, angelica, psoraleae, leech, and soil element; water extraction of astragalus, sclera, natural copper, and eucommia; then mixed with crushed notoginseng and cinnamon, spray-dried and packed into capsules into medicine. It has a remarkable effect in the treatment of avascular necrosis of the femoral head, with a total effective rate of 88%; it can significantly improve the main symptoms and signs of the disease, such as hip pain, claudication, and dysfunction; It is easy to take, has no chemical sweetener, is suitable for any patient, and has not found any toxic side effects.

Description

(1) Technical field [0001] The invention discloses a medicine for treating avascular necrosis of the femoral head and a preparation method thereof. (2) Background technology [0002] Avascular necrosis of the femoral head (LNFH for short) is a difficult and frequently-occurring disease in the Department of Orthopedics and Traumatology. The main manifestations are fixed pain of hip joint, limited joint movement, claudication and muscle atrophy of lower extremity. In recent years, due to the abuse of hormones, the incidence of neck fractures has increased, and the incidence of this disease has also shown an upward trend. The Western medical viewpoint of its etiology is summarized as follows. 1. Trauma: Intracapsular femoral neck fracture, hip dislocation, iatrogenic injury, femoral head crush injury; 2. Embolism: Sickle cell anemia, fat embolism, decompression sickness; 3 .Bone marrow lesions: Gaucher disease, fatty marrow heterotopia, compartment syndrome, poisoning; 4. Id...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K33/26A61K35/62A61P19/08
Inventor 吴振平杨豪郭会卿
Owner 吴振平
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